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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUCKS1 All Species: 24.55
Human Site: T179 Identified Species: 60
UniProt: Q9H1E3 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1E3 NP_073568.2 243 27296 T179 P R L K A T V T P S P V K G K
Chimpanzee Pan troglodytes XP_514141 243 27342 T179 P R L K A T V T P S P V K G K
Rhesus Macaque Macaca mulatta XP_001100185 311 34457 L240 S K S K C N A L A T S M D S A
Dog Lupus familis XP_536103 297 32946 T233 P R L K A T V T P S P V K G K
Cat Felis silvestris
Mouse Mus musculus Q80XU3 234 26295 K171 R K E K K M P K P R L K A T V
Rat Rattus norvegicus Q9EPJ0 243 27122 T179 P R L K A T V T P S P V K G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508086 538 59213 T474 P R L K A T V T P S P V K G K
Chicken Gallus gallus NP_998746 292 32576 T228 P R L K A T V T P S P V K G K
Frog Xenopus laevis NP_001084711 293 32980 V229 A T V T P S P V K A K G K S R
Zebra Danio Brachydanio rerio NP_001004601 305 34125 S229 L K A T V N P S P M K G K G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 25 80.1 N.A. 92.1 95 N.A. 42.3 77.4 65.1 51.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 45 80.4 N.A. 93.8 97.1 N.A. 43.8 80.4 72 63.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 13.3 100 N.A. 100 100 6.6 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 20 100 N.A. 100 100 33.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 60 0 10 0 10 10 0 0 10 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 20 0 70 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 30 0 80 10 0 0 10 10 0 20 10 80 0 70 % K
% Leu: 10 0 60 0 0 0 0 10 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 10 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % N
% Pro: 60 0 0 0 10 0 30 0 80 0 60 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 60 0 0 0 0 0 0 0 10 0 0 0 0 10 % R
% Ser: 10 0 10 0 0 10 0 10 0 60 10 0 0 20 0 % S
% Thr: 0 10 0 20 0 60 0 60 0 10 0 0 0 10 0 % T
% Val: 0 0 10 0 10 0 60 10 0 0 0 60 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _