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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMX4
All Species:
16.36
Human Site:
S259
Identified Species:
36
UniProt:
Q9H1E5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1E5
NP_066979.2
349
38952
S259
N
E
E
E
N
K
D
S
L
V
D
D
E
E
E
Chimpanzee
Pan troglodytes
XP_001167731
321
35737
E251
D
E
D
E
A
E
E
E
E
E
E
D
N
L
A
Rhesus Macaque
Macaca mulatta
XP_001116009
349
38888
S259
N
E
E
E
N
K
D
S
L
V
D
D
E
E
E
Dog
Lupus familis
XP_534350
290
32746
A221
D
L
G
D
E
E
E
A
E
E
D
E
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0L0
335
37113
S255
N
E
E
E
N
K
D
S
L
V
D
D
E
E
E
Rat
Rattus norvegicus
NP_001093999
336
37522
S257
N
E
E
E
N
K
D
S
L
V
D
D
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514678
320
35758
S251
E
E
K
E
E
D
R
S
G
G
E
E
E
K
E
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121246
264
30361
F195
F
L
G
L
I
L
V
F
V
A
D
F
L
C
P
Zebra Danio
Brachydanio rerio
NP_001025330
277
31225
P208
L
I
A
D
C
I
W
P
S
R
P
K
R
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611838
323
36326
D254
G
D
A
E
E
N
D
D
E
Q
R
D
S
D
E
Honey Bee
Apis mellifera
XP_397478
291
33381
K222
P
V
V
L
Q
D
K
K
K
Q
K
E
G
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.9
97.1
67.3
N.A.
79.6
82.2
N.A.
53.2
N.A.
35.2
40.4
N.A.
31.2
31.5
N.A.
N.A.
Protein Similarity:
100
91.9
98.5
74.2
N.A.
86.5
87.9
N.A.
65.3
N.A.
51.8
55
N.A.
53
48.1
N.A.
N.A.
P-Site Identity:
100
20
100
20
N.A.
100
100
N.A.
33.3
N.A.
6.6
0
N.A.
26.6
0
N.A.
N.A.
P-Site Similarity:
100
53.3
100
66.6
N.A.
100
100
N.A.
60
N.A.
13.3
13.3
N.A.
40
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
10
0
0
10
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
19
10
10
19
0
19
46
10
0
0
55
55
0
10
10
% D
% Glu:
10
55
37
64
28
19
19
10
28
19
19
28
55
46
55
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
10
0
19
0
0
0
0
0
10
10
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
37
10
10
10
0
10
10
0
10
0
% K
% Leu:
10
19
0
19
0
10
0
0
37
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
37
0
0
0
37
10
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
19
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
10
0
0
10
10
0
10
10
0
% R
% Ser:
0
0
0
0
0
0
0
46
10
0
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
10
0
10
37
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _