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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMX4 All Species: 16.36
Human Site: S259 Identified Species: 36
UniProt: Q9H1E5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1E5 NP_066979.2 349 38952 S259 N E E E N K D S L V D D E E E
Chimpanzee Pan troglodytes XP_001167731 321 35737 E251 D E D E A E E E E E E D N L A
Rhesus Macaque Macaca mulatta XP_001116009 349 38888 S259 N E E E N K D S L V D D E E E
Dog Lupus familis XP_534350 290 32746 A221 D L G D E E E A E E D E E E D
Cat Felis silvestris
Mouse Mus musculus Q8C0L0 335 37113 S255 N E E E N K D S L V D D E E E
Rat Rattus norvegicus NP_001093999 336 37522 S257 N E E E N K D S L V D D E E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514678 320 35758 S251 E E K E E D R S G G E E E K E
Chicken Gallus gallus
Frog Xenopus laevis NP_001121246 264 30361 F195 F L G L I L V F V A D F L C P
Zebra Danio Brachydanio rerio NP_001025330 277 31225 P208 L I A D C I W P S R P K R R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611838 323 36326 D254 G D A E E N D D E Q R D S D E
Honey Bee Apis mellifera XP_397478 291 33381 K222 P V V L Q D K K K Q K E G S G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.9 97.1 67.3 N.A. 79.6 82.2 N.A. 53.2 N.A. 35.2 40.4 N.A. 31.2 31.5 N.A. N.A.
Protein Similarity: 100 91.9 98.5 74.2 N.A. 86.5 87.9 N.A. 65.3 N.A. 51.8 55 N.A. 53 48.1 N.A. N.A.
P-Site Identity: 100 20 100 20 N.A. 100 100 N.A. 33.3 N.A. 6.6 0 N.A. 26.6 0 N.A. N.A.
P-Site Similarity: 100 53.3 100 66.6 N.A. 100 100 N.A. 60 N.A. 13.3 13.3 N.A. 40 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 10 0 0 10 0 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 19 10 10 19 0 19 46 10 0 0 55 55 0 10 10 % D
% Glu: 10 55 37 64 28 19 19 10 28 19 19 28 55 46 55 % E
% Phe: 10 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % F
% Gly: 10 0 19 0 0 0 0 0 10 10 0 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 37 10 10 10 0 10 10 0 10 0 % K
% Leu: 10 19 0 19 0 10 0 0 37 0 0 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 37 0 0 0 37 10 0 0 0 0 0 0 10 0 0 % N
% Pro: 10 0 0 0 0 0 0 10 0 0 10 0 0 0 10 % P
% Gln: 0 0 0 0 10 0 0 0 0 19 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 10 0 0 10 10 0 10 10 0 % R
% Ser: 0 0 0 0 0 0 0 46 10 0 0 0 10 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 10 0 0 0 10 0 10 37 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _