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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASCC2
All Species:
12.12
Human Site:
S418
Identified Species:
29.63
UniProt:
Q9H1I8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1I8
NP_115580.2
757
86360
S418
A
T
D
A
K
D
P
S
V
I
E
E
P
N
G
Chimpanzee
Pan troglodytes
XP_515064
762
86955
S418
A
T
D
A
K
D
P
S
V
I
E
E
P
N
G
Rhesus Macaque
Macaca mulatta
XP_001107005
752
85670
S418
A
T
D
A
K
D
P
S
V
T
E
E
P
N
G
Dog
Lupus familis
XP_852447
753
85919
P418
T
T
D
A
K
D
P
P
V
A
E
D
P
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WR3
749
85634
P418
I
K
D
I
K
D
P
P
R
A
K
G
S
N
N
Rat
Rattus norvegicus
NP_001102561
749
85766
S418
I
K
D
I
K
D
P
S
R
A
K
D
S
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080879
731
83531
Q418
A
S
T
V
P
P
T
Q
T
S
P
K
G
A
T
Zebra Danio
Brachydanio rerio
NP_956736
768
87145
S420
S
F
P
S
A
I
S
S
S
N
H
R
A
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_570025
735
83110
G419
A
D
D
M
A
S
N
G
V
Q
V
T
G
N
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794144
820
89264
K415
P
R
K
P
P
T
P
K
S
A
T
T
P
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
97.8
91.4
N.A.
86.7
87
N.A.
N.A.
N.A.
61.1
55.8
N.A.
28.5
N.A.
N.A.
37.4
Protein Similarity:
100
99.2
98.6
95.6
N.A.
91.5
92.4
N.A.
N.A.
N.A.
75.1
73.8
N.A.
46.6
N.A.
N.A.
52.8
P-Site Identity:
100
100
93.3
73.3
N.A.
33.3
40
N.A.
N.A.
N.A.
6.6
6.6
N.A.
26.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
40
53.3
N.A.
N.A.
N.A.
20
20
N.A.
26.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
40
20
0
0
0
0
40
0
0
10
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
70
0
0
60
0
0
0
0
0
20
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
40
30
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
10
20
10
40
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
20
0
0
20
0
10
0
0
0
20
0
0
0
0
0
% I
% Lys:
0
20
10
0
60
0
0
10
0
0
20
10
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
0
70
20
% N
% Pro:
10
0
10
10
20
10
70
20
0
0
10
0
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
20
0
0
10
0
10
0
% R
% Ser:
10
10
0
10
0
10
10
50
20
10
0
0
20
0
0
% S
% Thr:
10
40
10
0
0
10
10
0
10
10
10
20
0
0
10
% T
% Val:
0
0
0
10
0
0
0
0
50
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _