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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPF3A All Species: 3.64
Human Site: S21 Identified Species: 8
UniProt: Q9H1J1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1J1 NP_075387.1 476 54696 S21 A V A A R G P S G R E K L S A
Chimpanzee Pan troglodytes XP_509755 451 51775 P27 S V A R P A P P G L P C S S A
Rhesus Macaque Macaca mulatta XP_001107426 426 49069 R25 P G A S R A S R T R T G R D G
Dog Lupus familis XP_849752 441 51634 S21 A V P G R G P S G R E R Q S A
Cat Felis silvestris
Mouse Mus musculus NP_080200 422 48735 P19 A A L A A R G P S W R E K L S
Rat Rattus norvegicus NP_001012159 405 46742 P19 A V L S A R G P S W R E K L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506340 379 45295
Chicken Gallus gallus XP_416933 538 62539 E68 R G G G G G R E K R S M E V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0S733 452 54077 E18 S R E R G S V E I Q F R D C Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624605 551 65167 M37 K K E K C R P M T K V V I R R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780145 321 38755
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 77 68 N.A. 64.9 63.4 N.A. 57.5 60 N.A. 54.4 N.A. N.A. 32.1 N.A. 33.6
Protein Similarity: 100 83.4 79.8 77 N.A. 75 72.6 N.A. 67.4 72.1 N.A. 70.5 N.A. N.A. 49 N.A. 48.3
P-Site Identity: 100 40 20 73.3 N.A. 13.3 13.3 N.A. 0 13.3 N.A. 0 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 46.6 26.6 80 N.A. 26.6 33.3 N.A. 0 13.3 N.A. 20 N.A. N.A. 20 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 10 28 19 19 19 0 0 0 0 0 0 0 0 28 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 10 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % D
% Glu: 0 0 19 0 0 0 0 19 0 0 19 19 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 19 10 19 19 28 19 0 28 0 0 10 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % I
% Lys: 10 10 0 10 0 0 0 0 10 10 0 10 19 0 0 % K
% Leu: 0 0 19 0 0 0 0 0 0 10 0 0 10 19 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 10 0 10 0 37 28 0 0 10 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 10 % Q
% Arg: 10 10 0 19 28 28 10 10 0 37 19 19 10 10 10 % R
% Ser: 19 0 0 19 0 10 10 19 19 0 10 0 10 28 19 % S
% Thr: 0 0 0 0 0 0 0 0 19 0 10 0 0 0 0 % T
% Val: 0 37 0 0 0 0 10 0 0 0 10 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _