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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPF3A All Species: 12.12
Human Site: S341 Identified Species: 26.67
UniProt: Q9H1J1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1J1 NP_075387.1 476 54696 S341 Q E T S H S G S D K E H R D V
Chimpanzee Pan troglodytes XP_509755 451 51775 S316 Q E T S H S G S D K E H R D V
Rhesus Macaque Macaca mulatta XP_001107426 426 49069 S291 Q E T S R S G S D K E Y R D V
Dog Lupus familis XP_849752 441 51634 E298 E P T E K P K E R G E E V D V
Cat Felis silvestris
Mouse Mus musculus NP_080200 422 48735 G303 K E R G E A V G A G D E K Q E
Rat Rattus norvegicus NP_001012159 405 46742 H295 E E A T T E K H K E R G E A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506340 379 45295 K269 G P G G V K T K S L E S S V K
Chicken Gallus gallus XP_416933 538 62539 S388 K E K S Q N D S D K E Q R D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0S733 452 54077 M306 S K D N R S Q M E N D K E Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624605 551 65167 K369 F D G K D D R K Y D F K E D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780145 321 38755 D211 K S G K E K E D K D K G K G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 77 68 N.A. 64.9 63.4 N.A. 57.5 60 N.A. 54.4 N.A. N.A. 32.1 N.A. 33.6
Protein Similarity: 100 83.4 79.8 77 N.A. 75 72.6 N.A. 67.4 72.1 N.A. 70.5 N.A. N.A. 49 N.A. 48.3
P-Site Identity: 100 100 86.6 26.6 N.A. 6.6 13.3 N.A. 6.6 53.3 N.A. 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 93.3 33.3 N.A. 33.3 33.3 N.A. 6.6 73.3 N.A. 33.3 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 10 0 0 10 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 0 10 10 10 10 37 19 19 0 0 55 0 % D
% Glu: 19 55 0 10 19 10 10 10 10 10 55 19 28 0 10 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 0 28 19 0 0 28 10 0 19 0 19 0 10 0 % G
% His: 0 0 0 0 19 0 0 10 0 0 0 19 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 28 10 10 19 10 19 19 19 19 37 10 19 19 0 19 % K
% Leu: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % N
% Pro: 0 19 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 28 0 0 0 10 0 10 0 0 0 0 10 0 19 0 % Q
% Arg: 0 0 10 0 19 0 10 0 10 0 10 0 37 0 10 % R
% Ser: 10 10 0 37 0 37 0 37 10 0 0 10 10 0 0 % S
% Thr: 0 0 37 10 10 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 10 0 0 0 0 0 10 10 46 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _