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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPF3A All Species: 12.73
Human Site: S379 Identified Species: 28
UniProt: Q9H1J1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1J1 NP_075387.1 476 54696 S379 H H E P E R L S R R S E D E Q
Chimpanzee Pan troglodytes XP_509755 451 51775 S354 H H G P E R L S R R S E D E Q
Rhesus Macaque Macaca mulatta XP_001107426 426 49069 S329 H H E P D W L S R R S E D E Q
Dog Lupus familis XP_849752 441 51634 S335 L E K P R K K S Q N D S D K E
Cat Felis silvestris
Mouse Mus musculus NP_080200 422 48735 S338 K E P R D K R S R E K D P E T
Rat Rattus norvegicus NP_001012159 405 46742 D330 E R L Q D G S D K E P R D K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506340 379 45295 R304 F C E R E P E R Q R Y R S D D
Chicken Gallus gallus XP_416933 538 62539 V427 H Y E F D K F V R R N E E E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0S733 452 54077 M345 H Y E F D K F M R R K E E T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624605 551 65167 N417 S Y E N I K E N E E S M D D K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780145 321 38755 P246 N K G S D S H P D R D K K R D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.6 77 68 N.A. 64.9 63.4 N.A. 57.5 60 N.A. 54.4 N.A. N.A. 32.1 N.A. 33.6
Protein Similarity: 100 83.4 79.8 77 N.A. 75 72.6 N.A. 67.4 72.1 N.A. 70.5 N.A. N.A. 49 N.A. 48.3
P-Site Identity: 100 93.3 86.6 20 N.A. 20 6.6 N.A. 20 40 N.A. 33.3 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 100 93.3 93.3 53.3 N.A. 40 33.3 N.A. 33.3 73.3 N.A. 66.6 N.A. N.A. 53.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 55 0 0 10 10 0 19 10 55 19 19 % D
% Glu: 10 19 55 0 28 0 19 0 10 28 0 46 19 46 10 % E
% Phe: 10 0 0 19 0 0 19 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 19 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 46 28 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 10 10 0 0 46 10 0 10 0 19 10 10 19 19 % K
% Leu: 10 0 10 0 0 0 28 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 10 0 10 10 0 0 0 0 % N
% Pro: 0 0 10 37 0 10 0 10 0 0 10 0 10 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 19 0 0 0 0 0 28 % Q
% Arg: 0 10 0 19 10 19 10 10 55 64 0 19 0 10 10 % R
% Ser: 10 0 0 10 0 10 10 46 0 0 37 10 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 28 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _