Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ISCU All Species: 22.73
Human Site: Y35 Identified Species: 50
UniProt: Q9H1K1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1K1 NP_055116.1 167 17937 Y35 L S A P A R L Y H K K V V D H
Chimpanzee Pan troglodytes XP_001149059 167 17989 Y35 L S A P A R L Y H K K V V D H
Rhesus Macaque Macaca mulatta XP_001103180 167 17890 Y35 L S A P A R L Y H K K V V D H
Dog Lupus familis XP_534722 167 17962 Y35 L S A P A R L Y H K K V V D H
Cat Felis silvestris
Mouse Mus musculus Q9D7P6 168 18079 Y36 L S A P A R L Y H K K V V D H
Rat Rattus norvegicus NP_001099406 167 17948 Y35 L S A P A R L Y H K K V V D H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507819 225 23900 A88 R A N G R A N A P A Q V V D H
Chicken Gallus gallus
Frog Xenopus laevis NP_001080701 158 17023 N37 K V V D H Y E N P R N V G S L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649840 154 16699 N29 P V A L Y H E N V V E H Y E N
Honey Bee Apis mellifera XP_392655 165 17831 P29 V P A V F Y H P N V I D H Y E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12056 156 16911 N37 K V I D H Y T N P R N V G S M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 99.4 98.8 N.A. 96.4 97 N.A. 64 N.A. 72.4 N.A. N.A. 72.4 68.8 N.A. N.A.
Protein Similarity: 100 98.8 99.4 98.8 N.A. 97 97.5 N.A. 67.5 N.A. 80.2 N.A. N.A. 79.6 80.8 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 26.6 N.A. 6.6 N.A. N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 40 N.A. 13.3 N.A. N.A. 26.6 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 60.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 73 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 73 0 55 10 0 10 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 0 0 0 0 0 0 10 0 64 0 % D
% Glu: 0 0 0 0 0 0 19 0 0 0 10 0 0 10 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 19 0 0 % G
% His: 0 0 0 0 19 10 10 0 55 0 0 10 10 0 64 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 19 0 0 0 0 0 0 0 0 55 55 0 0 0 0 % K
% Leu: 55 0 0 10 0 0 55 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 10 0 0 0 10 28 10 0 19 0 0 0 10 % N
% Pro: 10 10 0 55 0 0 0 10 28 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 10 0 0 0 10 55 0 0 0 19 0 0 0 0 0 % R
% Ser: 0 55 0 0 0 0 0 0 0 0 0 0 0 19 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 10 28 10 10 0 0 0 0 10 19 0 82 64 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 28 0 55 0 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _