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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MESDC1
All Species:
18.18
Human Site:
S205
Identified Species:
57.14
UniProt:
Q9H1K6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1K6
NP_072088.1
362
37758
S205
C
A
L
A
S
D
K
S
R
D
R
F
S
R
E
Chimpanzee
Pan troglodytes
XP_510543
362
37726
S205
C
A
L
A
S
D
K
S
R
D
R
F
S
R
E
Rhesus Macaque
Macaca mulatta
XP_001109814
362
37784
S205
C
A
L
A
S
D
K
S
R
D
R
F
S
R
E
Dog
Lupus familis
XP_545882
363
37845
S206
C
A
L
A
S
D
K
S
R
D
R
F
S
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERE8
362
37768
S205
C
A
L
A
S
D
K
S
R
D
R
F
S
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512351
167
17287
R13
A
S
E
G
S
R
D
R
F
A
R
E
Q
F
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337121
354
37997
K200
A
S
D
K
S
K
D
K
F
A
K
E
Q
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794367
340
36842
V186
A
S
E
A
S
D
E
V
F
H
K
E
Q
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
97.5
N.A.
98
N.A.
N.A.
40.8
N.A.
N.A.
70.4
N.A.
N.A.
N.A.
N.A.
43.3
Protein Similarity:
100
99.7
99.7
98.3
N.A.
98.6
N.A.
N.A.
42.8
N.A.
N.A.
81.7
N.A.
N.A.
N.A.
N.A.
61.6
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
26.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
63
0
75
0
0
0
0
0
25
0
0
0
0
0
% A
% Cys:
63
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
75
25
0
0
63
0
0
0
0
0
% D
% Glu:
0
0
25
0
0
0
13
0
0
0
0
38
0
0
63
% E
% Phe:
0
0
0
0
0
0
0
0
38
0
0
63
0
38
0
% F
% Gly:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
13
63
13
0
0
25
0
0
0
38
% K
% Leu:
0
0
63
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% Q
% Arg:
0
0
0
0
0
13
0
13
63
0
75
0
0
63
0
% R
% Ser:
0
38
0
0
100
0
0
63
0
0
0
0
63
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _