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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG5
All Species:
34.24
Human Site:
T249
Identified Species:
53.81
UniProt:
Q9H1Y0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1Y0
NP_004840.1
275
32447
T249
G
I
E
P
M
L
E
T
P
L
Q
W
L
S
E
Chimpanzee
Pan troglodytes
XP_001144721
237
28161
P212
I
E
P
M
L
E
T
P
L
Q
W
L
S
E
H
Rhesus Macaque
Macaca mulatta
XP_001087825
249
29319
E221
T
L
G
D
L
L
K
E
V
C
P
S
A
I
D
Dog
Lupus familis
XP_854294
275
32353
T249
G
I
E
P
M
L
E
T
P
L
Q
W
L
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99J83
275
32384
T249
G
I
E
P
M
L
E
T
P
L
Q
W
L
S
E
Rat
Rattus norvegicus
Q3MQ06
275
32380
T249
G
I
E
P
L
L
E
T
P
L
Q
W
L
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512232
230
26918
A205
F
Q
D
C
P
L
L
A
S
K
Q
G
L
G
T
Chicken
Gallus gallus
NP_001006409
275
32460
T249
G
I
E
P
M
L
E
T
P
L
Q
W
L
S
E
Frog
Xenopus laevis
NP_001085331
306
35845
T280
G
I
E
P
M
L
E
T
P
V
Q
W
L
S
E
Zebra Danio
Brachydanio rerio
NP_991181
275
32097
T249
G
I
E
P
L
L
E
T
P
I
Q
W
L
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W3R7
269
31450
T244
G
I
D
L
H
E
E
T
Q
L
Q
W
M
S
E
Honey Bee
Apis mellifera
XP_623456
265
31393
P239
V
F
T
H
G
I
T
P
P
L
E
T
P
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204016
250
29681
T221
G
I
E
T
P
R
D
T
P
V
Q
W
L
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FFI2
337
38459
I310
G
I
E
M
K
L
E
I
P
F
S
W
V
V
N
Baker's Yeast
Sacchar. cerevisiae
Q12380
294
33541
M261
G
I
E
I
P
W
H
M
L
L
Y
D
L
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.1
86.9
99.2
N.A.
96.7
95.2
N.A.
72.3
89.8
76.4
80.3
N.A.
48
53.8
N.A.
48
Protein Similarity:
100
86.1
88.3
99.6
N.A.
99.2
98.5
N.A.
76
96.7
83.3
90.5
N.A.
68
72.3
N.A.
66.5
P-Site Identity:
100
0
6.6
100
N.A.
100
93.3
N.A.
20
100
93.3
86.6
N.A.
60
13.3
N.A.
66.6
P-Site Similarity:
100
6.6
33.3
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
73.3
33.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
14
7
0
0
7
0
0
0
0
7
0
0
7
% D
% Glu:
0
7
67
0
0
14
60
7
0
0
7
0
0
7
60
% E
% Phe:
7
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
74
0
7
0
7
0
0
0
0
0
0
7
0
7
0
% G
% His:
0
0
0
7
7
0
7
0
0
0
0
0
0
0
7
% H
% Ile:
7
74
0
7
0
7
0
7
0
7
0
0
0
7
0
% I
% Lys:
0
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% K
% Leu:
0
7
0
7
27
67
7
0
14
54
0
7
67
7
0
% L
% Met:
0
0
0
14
34
0
0
7
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
7
47
20
0
0
14
67
0
7
0
7
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
7
7
67
0
0
0
7
% Q
% Arg:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
7
0
7
7
7
60
7
% S
% Thr:
7
0
7
7
0
0
14
60
0
0
0
7
0
0
7
% T
% Val:
7
0
0
0
0
0
0
0
7
14
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
7
67
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _