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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG5
All Species:
28.18
Human Site:
Y184
Identified Species:
44.29
UniProt:
Q9H1Y0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1Y0
NP_004840.1
275
32447
Y184
A
E
E
N
G
F
R
Y
I
P
F
R
I
Y
Q
Chimpanzee
Pan troglodytes
XP_001144721
237
28161
I161
T
T
T
E
R
P
F
I
Q
K
L
F
R
P
V
Rhesus Macaque
Macaca mulatta
XP_001087825
249
29319
A167
D
R
F
D
Q
F
W
A
I
N
R
K
L
M
E
Dog
Lupus familis
XP_854294
275
32353
Y184
A
E
E
N
G
F
R
Y
I
P
F
R
I
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99J83
275
32384
Y184
P
E
E
N
G
F
R
Y
I
P
F
R
I
Y
Q
Rat
Rattus norvegicus
Q3MQ06
275
32380
Y184
P
E
E
N
G
F
R
Y
I
P
F
R
I
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512232
230
26918
W154
K
K
D
H
K
Q
L
W
M
G
L
Q
N
D
K
Chicken
Gallus gallus
NP_001006409
275
32460
Y184
P
E
D
S
G
F
R
Y
I
P
F
R
I
Y
Q
Frog
Xenopus laevis
NP_001085331
306
35845
Y215
P
E
D
G
G
F
R
Y
I
P
F
R
I
Y
Q
Zebra Danio
Brachydanio rerio
NP_991181
275
32097
Y186
T
E
E
G
G
F
R
Y
I
P
F
R
I
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W3R7
269
31450
N186
G
D
L
E
S
F
K
N
I
P
L
R
I
Y
T
Honey Bee
Apis mellifera
XP_623456
265
31393
Y187
N
I
E
E
G
F
K
Y
I
P
F
R
C
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001204016
250
29681
L170
I
F
Q
V
P
E
K
L
H
T
Q
R
L
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FFI2
337
38459
R166
G
D
L
D
A
Y
T
R
L
S
P
K
L
K
M
Baker's Yeast
Sacchar. cerevisiae
Q12380
294
33541
H199
I
S
S
S
R
P
R
H
I
P
L
I
I
Q
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.1
86.9
99.2
N.A.
96.7
95.2
N.A.
72.3
89.8
76.4
80.3
N.A.
48
53.8
N.A.
48
Protein Similarity:
100
86.1
88.3
99.6
N.A.
99.2
98.5
N.A.
76
96.7
83.3
90.5
N.A.
68
72.3
N.A.
66.5
P-Site Identity:
100
0
13.3
100
N.A.
93.3
93.3
N.A.
0
80
80
86.6
N.A.
40
60
N.A.
6.6
P-Site Similarity:
100
0
40
100
N.A.
93.3
93.3
N.A.
46.6
93.3
86.6
86.6
N.A.
53.3
66.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.1
40.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
7
14
20
14
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
47
40
20
0
7
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
7
7
0
0
67
7
0
0
0
54
7
0
7
0
% F
% Gly:
14
0
0
14
54
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
7
7
0
0
0
0
0
0
% H
% Ile:
14
7
0
0
0
0
0
7
74
0
0
7
60
0
0
% I
% Lys:
7
7
0
0
7
0
20
0
0
7
0
14
0
7
14
% K
% Leu:
0
0
14
0
0
0
7
7
7
0
27
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
7
% M
% Asn:
7
0
0
27
0
0
0
7
0
7
0
0
7
0
0
% N
% Pro:
27
0
0
0
7
14
0
0
0
67
7
0
0
7
0
% P
% Gln:
0
0
7
0
7
7
0
0
7
0
7
7
0
7
47
% Q
% Arg:
0
7
0
0
14
0
54
7
0
0
7
67
7
0
0
% R
% Ser:
0
7
7
14
7
0
0
0
0
7
0
0
0
0
0
% S
% Thr:
14
7
7
0
0
0
7
0
0
7
0
0
0
0
20
% T
% Val:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
54
0
0
0
0
0
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _