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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATG5 All Species: 44.24
Human Site: Y44 Identified Species: 69.52
UniProt: Q9H1Y0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H1Y0 NP_004840.1 275 32447 Y44 L L L P R V S Y L T L V T D K
Chimpanzee Pan troglodytes XP_001144721 237 28161 Y44 L L L P R V S Y L T L V T D K
Rhesus Macaque Macaca mulatta XP_001087825 249 29319 Y44 L L L P R V S Y L T L V T D K
Dog Lupus familis XP_854294 275 32353 Y44 L L L P R V S Y L T L V T D K
Cat Felis silvestris
Mouse Mus musculus Q99J83 275 32384 Y44 L L L P R V S Y L T L V T D K
Rat Rattus norvegicus Q3MQ06 275 32380 Y44 L L L P R V S Y L T L V T D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512232 230 26918 L37 R E A E P Y Y L L L P R V S Y
Chicken Gallus gallus NP_001006409 275 32460 Y44 L L L P R I S Y L T L V T D K
Frog Xenopus laevis NP_001085331 306 35845 C44 S R P R T S C C A A T L Q T R
Zebra Danio Brachydanio rerio NP_991181 275 32097 Y46 L L L P R V S Y L T L V T D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W3R7 269 31450 Y44 L M I S R L S Y L P L V T D K
Honey Bee Apis mellifera XP_623456 265 31393 Y45 L M V P R L S Y F P L C T D K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001204016 250 29681 W44 I D E Q D E V W F E S N G Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FFI2 337 38459 Y43 V L A P R I G Y L P L L I P L
Baker's Yeast Sacchar. cerevisiae Q12380 294 33541 Y44 I R V P R E T Y L V N Y M P L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.1 86.9 99.2 N.A. 96.7 95.2 N.A. 72.3 89.8 76.4 80.3 N.A. 48 53.8 N.A. 48
Protein Similarity: 100 86.1 88.3 99.6 N.A. 99.2 98.5 N.A. 76 96.7 83.3 90.5 N.A. 68 72.3 N.A. 66.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 93.3 0 100 N.A. 66.6 60 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 13.3 100 N.A. 86.6 80 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 27 22.7 N.A.
Protein Similarity: N.A. N.A. N.A. 47.1 40.1 N.A.
P-Site Identity: N.A. N.A. N.A. 40 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 0 0 0 0 7 7 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 7 7 0 0 0 7 0 0 0 % C
% Asp: 0 7 0 0 7 0 0 0 0 0 0 0 0 67 0 % D
% Glu: 0 7 7 7 0 14 0 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 0 7 0 0 14 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % K
% Leu: 67 60 54 0 0 14 0 7 80 7 74 14 0 0 14 % L
% Met: 0 14 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % N
% Pro: 0 0 7 74 7 0 0 0 0 20 7 0 0 14 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 7 7 0 % Q
% Arg: 7 14 0 7 80 0 0 0 0 0 0 7 0 0 7 % R
% Ser: 7 0 0 7 0 7 67 0 0 0 7 0 0 7 0 % S
% Thr: 0 0 0 0 7 0 7 0 0 54 7 0 67 7 0 % T
% Val: 7 0 14 0 0 47 7 0 0 7 0 60 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 7 80 0 0 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _