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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCG8 All Species: 8.48
Human Site: T39 Identified Species: 31.11
UniProt: Q9H221 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H221 NP_071882.1 673 75679 T39 S D N S L Y F T Y S G Q P N T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta Q5MB13 654 72441 F31 T S N D R K A F T E G A V L S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9DBM0 673 75977 T40 S D N S L Y F T Y S G Q S N T
Rat Rattus norvegicus P58428 694 78218 T39 S D N S L Y F T Y S G Q S N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10090 687 75654 G38 S Q S C I N Q G F G Q A K N Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11180 598 66888 G20 V S G M A E S G K L L A I L G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6W5 648 72600 A34 T Q S K S V L A F P T I T S Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 28.2 N.A. N.A. 81.7 77.3 N.A. N.A. N.A. N.A. N.A. N.A. 28.9 N.A. 26.1 N.A.
Protein Similarity: 100 N.A. 49.3 N.A. N.A. 89.4 85.5 N.A. N.A. N.A. N.A. N.A. N.A. 48.7 N.A. 43.5 N.A.
P-Site Identity: 100 N.A. 13.3 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 N.A. 26.6 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 33.3 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 15 15 0 0 0 43 0 0 0 % A
% Cys: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 43 0 15 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 15 0 0 0 15 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 43 15 29 0 0 0 0 0 0 % F
% Gly: 0 0 15 0 0 0 0 29 0 15 58 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 15 0 0 0 0 0 0 15 15 0 0 % I
% Lys: 0 0 0 15 0 15 0 0 15 0 0 0 15 0 0 % K
% Leu: 0 0 0 0 43 0 15 0 0 15 15 0 0 29 0 % L
% Met: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 58 0 0 15 0 0 0 0 0 0 0 58 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 15 0 0 15 0 0 % P
% Gln: 0 29 0 0 0 0 15 0 0 0 15 43 0 0 15 % Q
% Arg: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 58 29 29 43 15 0 15 0 0 43 0 0 29 15 15 % S
% Thr: 29 0 0 0 0 0 0 43 15 0 15 0 15 0 43 % T
% Val: 15 0 0 0 0 15 0 0 0 0 0 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 43 0 0 43 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _