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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG5
All Species:
5.76
Human Site:
S21
Identified Species:
12.67
UniProt:
Q9H222
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H222
NP_071881.1
651
72504
S21
G
L
Q
V
N
R
G
S
Q
S
S
L
E
G
A
Chimpanzee
Pan troglodytes
XP_525745
673
75530
Y40
D
N
S
L
Y
F
T
Y
S
G
Q
P
N
T
L
Rhesus Macaque
Macaca mulatta
XP_001111277
651
72941
S21
G
L
Q
V
N
R
G
S
Q
S
S
L
E
G
A
Dog
Lupus familis
XP_538475
652
73324
Q22
I
Q
V
S
R
G
P
Q
S
S
P
E
D
V
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_114090
652
73226
L22
P
H
I
N
R
G
S
L
S
S
L
E
Q
G
S
Rat
Rattus norvegicus
NP_446206
652
73354
Q22
P
H
N
N
R
G
S
Q
S
S
L
E
E
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521051
388
42463
Chicken
Gallus gallus
XP_419457
645
72537
V24
Q
A
G
E
T
E
A
V
A
Q
P
P
N
S
I
Frog
Xenopus laevis
NP_001091141
661
73548
K22
P
L
A
N
G
E
V
K
K
K
G
L
K
K
K
Zebra Danio
Brachydanio rerio
NP_001122162
652
73168
E25
G
S
F
K
V
V
S
E
M
E
T
A
R
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002314895
683
75955
T25
G
P
S
N
V
M
L
T
N
W
T
E
T
V
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.7
94
84.3
N.A.
80
79.2
N.A.
40.4
62.8
29.6
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.7
96.9
91.2
N.A.
89.8
89.7
N.A.
48.5
78.6
52.1
76.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
6.6
N.A.
13.3
20
N.A.
0
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
13.3
N.A.
26.6
26.6
N.A.
0
0
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
28.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
10
0
10
0
0
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
10
0
19
0
10
0
10
0
37
28
0
0
% E
% Phe:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
0
10
0
10
28
19
0
0
10
10
0
0
37
0
% G
% His:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
10
0
0
0
10
10
10
0
0
10
10
10
% K
% Leu:
0
28
0
10
0
0
10
10
0
0
19
28
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
10
37
19
0
0
0
10
0
0
0
19
0
10
% N
% Pro:
28
10
0
0
0
0
10
0
0
0
19
19
0
0
10
% P
% Gln:
10
10
19
0
0
0
0
19
19
10
10
0
10
0
0
% Q
% Arg:
0
0
0
0
28
19
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
10
19
10
0
0
28
19
37
46
19
0
0
19
19
% S
% Thr:
0
0
0
0
10
0
10
10
0
0
19
0
10
10
10
% T
% Val:
0
0
10
19
19
10
10
10
0
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _