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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG5
All Species:
23.03
Human Site:
S319
Identified Species:
50.67
UniProt:
Q9H222
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H222
NP_071881.1
651
72504
S319
K
E
R
E
I
E
T
S
K
R
V
Q
M
I
E
Chimpanzee
Pan troglodytes
XP_525745
673
75530
R339
R
E
Q
E
L
A
T
R
E
K
A
Q
S
L
A
Rhesus Macaque
Macaca mulatta
XP_001111277
651
72941
Y319
K
E
R
E
I
E
T
Y
K
R
V
Q
M
I
E
Dog
Lupus familis
XP_538475
652
73324
Y320
K
E
R
E
L
E
T
Y
K
R
V
Q
M
I
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_114090
652
73226
Y320
R
E
R
E
I
E
T
Y
K
R
V
Q
M
L
E
Rat
Rattus norvegicus
NP_446206
652
73354
Y320
R
E
R
E
I
E
T
Y
K
R
V
Q
M
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521051
388
42463
R72
L
L
G
Y
L
T
V
R
E
T
L
M
Y
T
A
Chicken
Gallus gallus
XP_419457
645
72537
Y312
K
E
R
E
L
E
T
Y
S
R
V
Q
V
I
I
Frog
Xenopus laevis
NP_001091141
661
73548
E310
V
A
L
N
K
L
E
E
V
E
L
E
N
V
Q
Zebra Danio
Brachydanio rerio
NP_001122162
652
73168
Y323
S
E
R
E
A
A
T
Y
R
R
M
H
D
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002314895
683
75955
Q356
D
T
R
S
Q
D
D
Q
L
E
F
H
G
R
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.7
94
84.3
N.A.
80
79.2
N.A.
40.4
62.8
29.6
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.7
96.9
91.2
N.A.
89.8
89.7
N.A.
48.5
78.6
52.1
76.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
93.3
86.6
N.A.
80
80
N.A.
0
66.6
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
93.3
93.3
N.A.
93.3
93.3
N.A.
20
80
26.6
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
28.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
19
0
0
0
0
10
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
10
0
0
0
0
0
10
0
0
% D
% Glu:
0
73
0
73
0
55
10
10
19
19
0
10
0
0
46
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% H
% Ile:
0
0
0
0
37
0
0
0
0
0
0
0
0
46
10
% I
% Lys:
37
0
0
0
10
0
0
0
46
10
0
0
0
0
0
% K
% Leu:
10
10
10
0
37
10
0
0
10
0
19
0
0
28
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
10
46
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
0
0
10
0
0
0
64
0
0
10
% Q
% Arg:
28
0
73
0
0
0
0
19
10
64
0
0
0
10
0
% R
% Ser:
10
0
0
10
0
0
0
10
10
0
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
10
73
0
0
10
0
0
0
10
10
% T
% Val:
10
0
0
0
0
0
10
0
10
0
55
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
55
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _