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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCG5 All Species: 14.24
Human Site: S37 Identified Species: 31.33
UniProt: Q9H222 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H222 NP_071881.1 651 72504 S37 A T A P E P H S L G I L H A S
Chimpanzee Pan troglodytes XP_525745 673 75530 V56 V R D L N Y Q V D L A S Q V P
Rhesus Macaque Macaca mulatta XP_001111277 651 72941 S37 A T A L E P H S L G I L H A S
Dog Lupus familis XP_538475 652 73324 S38 A V S K P R H S L G I L H V S
Cat Felis silvestris
Mouse Mus musculus NP_114090 652 73226 S38 T G T E A R H S L G V L H V S
Rat Rattus norvegicus NP_446206 652 73354 S38 T G S E A R H S L G V L N V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521051 388 42463
Chicken Gallus gallus XP_419457 645 72537 V40 V R G V S Y S V R V N V G P W
Frog Xenopus laevis NP_001091141 661 73548 Y38 S G A V L S F Y N I N Y K V K
Zebra Danio Brachydanio rerio NP_001122162 652 73168 C41 D Y I E P S S C L S V K N V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002314895 683 75955 S41 H A E P S V S S S I N N T S S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.7 94 84.3 N.A. 80 79.2 N.A. 40.4 62.8 29.6 60.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 49.7 96.9 91.2 N.A. 89.8 89.7 N.A. 48.5 78.6 52.1 76.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 60 N.A. 46.6 40 N.A. 0 0 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 93.3 66.6 N.A. 53.3 60 N.A. 0 6.6 13.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 28.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 48.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 10 28 0 19 0 0 0 0 0 10 0 0 19 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 10 28 19 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 28 10 0 0 0 0 0 0 46 0 0 10 0 0 % G
% His: 10 0 0 0 0 0 46 0 0 0 0 0 37 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 19 28 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 10 10 0 10 % K
% Leu: 0 0 0 19 10 0 0 0 55 10 0 46 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 10 0 28 10 19 0 0 % N
% Pro: 0 0 0 19 19 19 0 0 0 0 0 0 0 10 10 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 0 19 0 0 0 28 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 0 19 0 19 19 28 55 10 10 0 10 0 10 64 % S
% Thr: 19 19 10 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 19 10 0 19 0 10 0 19 0 10 28 10 0 55 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 10 0 0 0 19 0 10 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _