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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCG5 All Species: 31.21
Human Site: T305 Identified Species: 68.67
UniProt: Q9H222 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H222 NP_071881.1 651 72504 T305 F D F Y M D L T S V D T Q S K
Chimpanzee Pan troglodytes XP_525745 673 75530 T325 A D F Y V D L T S I D R R S R
Rhesus Macaque Macaca mulatta XP_001111277 651 72941 T305 F D F Y M D L T S V D T Q S K
Dog Lupus familis XP_538475 652 73324 T306 F D F Y M D L T S V D T Q S K
Cat Felis silvestris
Mouse Mus musculus NP_114090 652 73226 T306 F D F Y M D L T S V D T Q S R
Rat Rattus norvegicus NP_446206 652 73354 T306 F D F Y M D L T S V D T Q S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521051 388 42463 Y58 R F Q D C I S Y A L Q E D T L
Chicken Gallus gallus XP_419457 645 72537 T298 F D F Y V D L T S V D T R S K
Frog Xenopus laevis NP_001091141 661 73548 I296 A D F F L D I I N G D S T A V
Zebra Danio Brachydanio rerio NP_001122162 652 73168 T309 F D I Y V D L T S V D T R C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002314895 683 75955 L342 P A D F L L D L A N G L V P D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 27.7 94 84.3 N.A. 80 79.2 N.A. 40.4 62.8 29.6 60.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 49.7 96.9 91.2 N.A. 89.8 89.7 N.A. 48.5 78.6 52.1 76.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 60 100 100 N.A. 93.3 93.3 N.A. 0 86.6 26.6 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 100 100 N.A. 20 100 66.6 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 28.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 48.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 0 0 0 0 19 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 82 10 10 0 82 10 0 0 0 82 0 10 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 64 10 73 19 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 10 10 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37 % K
% Leu: 0 0 0 0 19 10 73 10 0 10 0 10 0 0 10 % L
% Met: 0 0 0 0 46 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 10 0 46 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 10 28 0 28 % R
% Ser: 0 0 0 0 0 0 10 0 73 0 0 10 0 64 10 % S
% Thr: 0 0 0 0 0 0 0 73 0 0 0 64 10 10 0 % T
% Val: 0 0 0 0 28 0 0 0 0 64 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 73 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _