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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG5
All Species:
24.24
Human Site:
T586
Identified Species:
53.33
UniProt:
Q9H222
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H222
NP_071881.1
651
72504
T586
E
F
Y
G
L
N
F
T
C
G
S
S
N
V
S
Chimpanzee
Pan troglodytes
XP_525745
673
75530
K614
Q
F
S
R
R
T
Y
K
M
P
L
G
N
L
T
Rhesus Macaque
Macaca mulatta
XP_001111277
651
72941
T586
E
F
Y
G
L
N
F
T
C
G
S
S
N
V
S
Dog
Lupus familis
XP_538475
652
73324
T587
E
F
Y
G
Q
N
F
T
C
G
S
S
N
G
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_114090
652
73226
T587
E
F
Y
G
L
N
F
T
C
G
G
S
N
T
S
Rat
Rattus norvegicus
NP_446206
652
73354
T587
E
F
Y
G
L
N
F
T
C
G
G
S
N
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521051
388
42463
C330
F
G
L
F
L
V
F
C
L
L
H
V
Q
S
D
Chicken
Gallus gallus
XP_419457
645
72537
T579
E
F
Y
G
L
N
F
T
C
G
K
D
N
S
S
Frog
Xenopus laevis
NP_001091141
661
73548
C592
E
F
T
N
L
N
F
C
R
S
N
N
T
S
I
Zebra Danio
Brachydanio rerio
NP_001122162
652
73168
T590
E
F
Y
G
L
N
F
T
C
T
P
I
A
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002314895
683
75955
Y615
K
Y
I
S
F
S
H
Y
C
Y
K
L
L
V
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.7
94
84.3
N.A.
80
79.2
N.A.
40.4
62.8
29.6
60.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.7
96.9
91.2
N.A.
89.8
89.7
N.A.
48.5
78.6
52.1
76.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
86.6
86.6
N.A.
13.3
80
33.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
100
86.6
N.A.
86.6
86.6
N.A.
13.3
80
46.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
28.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
19
73
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
82
0
10
10
0
82
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
64
0
0
0
0
0
55
19
10
0
19
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
10
0
0
0
0
0
0
10
0
0
19
0
0
0
0
% K
% Leu:
0
0
10
0
73
0
0
0
10
10
10
10
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
73
0
0
0
0
10
10
64
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
10
0
10
0
0
0
10
28
46
0
28
55
% S
% Thr:
0
0
10
0
0
10
0
64
0
10
0
0
10
19
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
10
0
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
64
0
0
0
10
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _