KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EHD4
All Species:
4.24
Human Site:
S390
Identified Species:
31.11
UniProt:
Q9H223
Number Species:
3
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H223
NP_644670.1
541
61175
S390
E
A
V
D
N
M
L
S
N
K
I
S
P
L
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQP2
541
61462
T390
E
A
V
D
N
M
L
T
N
K
I
S
S
L
M
Rat
Rattus norvegicus
Q8R491
535
60773
A387
E
V
V
D
D
M
L
A
H
D
I
A
Q
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90577
471
54129
L344
R
V
R
I
H
A
L
L
V
D
R
Y
L
Q
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
97
74.8
N.A.
N.A.
27.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
98.7
86.5
N.A.
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
86.6
53.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
93.3
80
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
25
0
25
0
0
0
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
75
25
0
0
0
0
50
0
0
0
0
0
% D
% Glu:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
25
0
0
0
25
0
0
0
0
0
0
% H
% Ile:
0
0
0
25
0
0
0
0
0
0
75
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
100
25
0
0
0
0
25
75
0
% L
% Met:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
75
% M
% Asn:
0
0
0
0
50
0
0
0
50
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
25
25
0
% Q
% Arg:
25
0
25
0
0
0
0
0
0
0
25
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
25
0
0
0
50
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
25
% T
% Val:
0
50
75
0
0
0
0
0
25
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _