KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PORCN
All Species:
15.15
Human Site:
S186
Identified Species:
41.67
UniProt:
Q9H237
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H237
NP_073736.2
461
52318
S186
A
V
Q
G
R
P
L
S
C
R
W
L
Q
K
V
Chimpanzee
Pan troglodytes
XP_521046
132
14657
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851011
461
52382
S186
A
V
Q
G
R
P
L
S
R
R
W
L
Q
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJJ7
461
52489
S186
A
V
Q
G
R
P
L
S
R
R
W
L
K
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513655
461
52848
S186
A
V
E
S
R
E
L
S
R
P
W
V
Q
K
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081423
461
52848
S186
A
V
K
G
Q
R
L
S
I
S
W
L
W
R
V
Zebra Danio
Brachydanio rerio
NP_001119953
442
50806
N174
F
G
P
W
I
S
F
N
S
Y
M
D
A
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VWV9
525
59176
W253
C
L
V
P
R
N
S
W
L
V
S
L
R
R
L
Honey Bee
Apis mellifera
XP_001121879
461
54654
C187
A
Y
M
G
Y
M
F
C
S
V
T
C
L
F
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.6
N.A.
98.6
N.A.
97.1
N.A.
N.A.
85.4
N.A.
76.5
66.1
N.A.
30.4
33.4
N.A.
N.A.
Protein Similarity:
100
28.6
N.A.
99.3
N.A.
98.6
N.A.
N.A.
92.4
N.A.
88
79.6
N.A.
44.5
53.1
N.A.
N.A.
P-Site Identity:
100
0
N.A.
93.3
N.A.
86.6
N.A.
N.A.
60
N.A.
53.3
0
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
0
N.A.
93.3
N.A.
93.3
N.A.
N.A.
73.3
N.A.
73.3
6.6
N.A.
40
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
12
0
0
0
0
0
0
12
12
0
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
12
% E
% Phe:
12
0
0
0
0
0
23
0
0
0
0
0
0
12
0
% F
% Gly:
0
12
0
56
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
12
0
0
0
0
0
0
0
0
0
12
45
0
% K
% Leu:
0
12
0
0
0
0
56
0
12
0
0
56
12
0
12
% L
% Met:
0
0
12
0
0
12
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
0
34
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
34
0
12
0
0
0
0
0
0
0
34
0
0
% Q
% Arg:
0
0
0
0
56
12
0
0
34
34
0
0
12
23
0
% R
% Ser:
0
0
0
12
0
12
12
56
23
12
12
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
56
12
0
0
0
0
0
0
23
0
12
0
12
56
% V
% Trp:
0
0
0
12
0
0
0
12
0
0
56
0
12
0
0
% W
% Tyr:
0
12
0
0
12
0
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _