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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PORCN All Species: 19.7
Human Site: S92 Identified Species: 54.17
UniProt: Q9H237 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H237 NP_073736.2 461 52318 S92 V L F L C R H S S H R G V F L
Chimpanzee Pan troglodytes XP_521046 132 14657
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851011 461 52382 S92 V L F L C R H S S H R G V F L
Cat Felis silvestris
Mouse Mus musculus Q9JJJ7 461 52489 S92 V L F L C R H S S H R G V F L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513655 461 52848 S92 V L F L C R H S A H R G V F L
Chicken Gallus gallus
Frog Xenopus laevis NP_001081423 461 52848 S92 V L F L C R H S Q H R G V L L
Zebra Danio Brachydanio rerio NP_001119953 442 50806 S79 M V W V V L L S L L C Y L I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VWV9 525 59176 G156 L L Q L L R L G R R G A Q V L
Honey Bee Apis mellifera XP_001121879 461 54654 I94 M L I G I C N I Y F Y V I E C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.6 N.A. 98.6 N.A. 97.1 N.A. N.A. 85.4 N.A. 76.5 66.1 N.A. 30.4 33.4 N.A. N.A.
Protein Similarity: 100 28.6 N.A. 99.3 N.A. 98.6 N.A. N.A. 92.4 N.A. 88 79.6 N.A. 44.5 53.1 N.A. N.A.
P-Site Identity: 100 0 N.A. 100 N.A. 100 N.A. N.A. 93.3 N.A. 86.6 13.3 N.A. 26.6 6.6 N.A. N.A.
P-Site Similarity: 100 0 N.A. 100 N.A. 100 N.A. N.A. 100 N.A. 86.6 46.6 N.A. 33.3 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 0 % A
% Cys: 0 0 0 0 56 12 0 0 0 0 12 0 0 0 12 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % E
% Phe: 0 0 56 0 0 0 0 0 0 12 0 0 0 45 0 % F
% Gly: 0 0 0 12 0 0 0 12 0 0 12 56 0 0 0 % G
% His: 0 0 0 0 0 0 56 0 0 56 0 0 0 0 0 % H
% Ile: 0 0 12 0 12 0 0 12 0 0 0 0 12 12 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 78 0 67 12 12 23 0 12 12 0 0 12 12 78 % L
% Met: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 12 0 0 0 0 0 12 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 0 67 0 0 12 12 56 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 67 34 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 56 12 0 12 12 0 0 0 0 0 0 12 56 12 0 % V
% Trp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 12 0 12 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _