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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS33B
All Species:
30.61
Human Site:
S417
Identified Species:
56.11
UniProt:
Q9H267
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H267
NP_061138.3
617
70615
S417
L
I
P
K
D
Y
R
S
L
K
T
Q
Y
L
Q
Chimpanzee
Pan troglodytes
XP_510601
617
70571
S417
L
I
P
K
D
Y
R
S
L
K
T
Q
Y
L
Q
Rhesus Macaque
Macaca mulatta
XP_001097946
616
70325
S417
L
I
P
K
D
Y
R
S
L
K
T
Q
Y
L
Q
Dog
Lupus familis
XP_536197
617
70646
S417
L
I
P
K
D
Y
R
S
L
K
T
Q
Y
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P59016
617
70508
S417
L
I
P
K
D
Y
R
S
L
K
T
Q
Y
L
Q
Rat
Rattus norvegicus
Q63616
617
70675
S417
L
I
P
K
D
Y
R
S
L
K
T
Q
Y
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506548
578
65937
I379
N
N
Y
I
E
D
C
I
A
Q
K
H
P
L
I
Chicken
Gallus gallus
NP_001026519
616
70047
S416
L
I
P
K
D
Y
R
S
L
K
T
Q
Y
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y1I2
617
68748
L417
L
I
A
C
R
V
E
L
N
R
V
L
R
L
I
Honey Bee
Apis mellifera
XP_395353
609
68702
P405
D
M
I
V
Q
Q
Q
P
L
L
K
V
L
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789858
623
70278
T424
L
P
S
K
E
Y
Q
T
L
Q
R
H
F
L
Q
Poplar Tree
Populus trichocarpa
XP_002316387
596
67323
R397
E
P
L
V
S
V
L
R
L
L
I
L
F
S
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KJ7
592
66894
N393
H
K
Q
E
P
L
T
N
V
L
R
L
L
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.4
97.5
N.A.
97.4
96.7
N.A.
30.6
81.6
N.A.
N.A.
N.A.
28
32
N.A.
46.7
Protein Similarity:
100
100
98.2
99
N.A.
98.8
98.2
N.A.
51.2
93.3
N.A.
N.A.
N.A.
50.4
54.1
N.A.
69.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
N.A.
N.A.
20
6.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
N.A.
N.A.
26.6
20
N.A.
73.3
Percent
Protein Identity:
29.5
N.A.
N.A.
29.3
N.A.
N.A.
Protein Similarity:
50
N.A.
N.A.
50.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
54
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
8
16
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% H
% Ile:
0
62
8
8
0
0
0
8
0
0
8
0
0
0
24
% I
% Lys:
0
8
0
62
0
0
0
0
0
54
16
0
0
0
0
% K
% Leu:
70
0
8
0
0
8
8
8
77
24
0
24
16
77
16
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
16
54
0
8
0
0
8
0
0
0
0
8
0
0
% P
% Gln:
0
0
8
0
8
8
16
0
0
16
0
54
0
0
62
% Q
% Arg:
0
0
0
0
8
0
54
8
0
8
16
0
8
8
0
% R
% Ser:
0
0
8
0
8
0
0
54
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
8
8
0
0
54
0
0
0
0
% T
% Val:
0
0
0
16
0
16
0
0
8
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
62
0
0
0
0
0
0
54
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _