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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS33B
All Species:
19.09
Human Site:
S533
Identified Species:
35
UniProt:
Q9H267
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H267
NP_061138.3
617
70615
S533
E
Q
V
L
E
R
R
S
W
Q
G
L
D
E
V
Chimpanzee
Pan troglodytes
XP_510601
617
70571
S533
E
Q
V
L
E
R
R
S
W
Q
G
L
D
E
V
Rhesus Macaque
Macaca mulatta
XP_001097946
616
70325
W533
Q
V
L
E
R
R
S
W
Q
G
L
D
E
V
V
Dog
Lupus familis
XP_536197
617
70646
S533
E
Q
V
L
E
R
R
S
W
Q
G
L
D
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P59016
617
70508
S533
E
Q
V
L
D
R
R
S
W
Q
G
L
D
E
V
Rat
Rattus norvegicus
Q63616
617
70675
S533
E
Q
V
L
D
R
R
S
W
Q
G
L
D
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506548
578
65937
E495
P
G
W
R
S
I
E
E
V
L
K
M
L
P
G
Chicken
Gallus gallus
NP_001026519
616
70047
G532
E
Q
V
L
E
R
R
G
W
Q
G
L
E
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y1I2
617
68748
P533
K
S
Q
I
N
N
L
P
G
P
T
F
E
D
F
Honey Bee
Apis mellifera
XP_395353
609
68702
L521
L
N
D
V
M
G
L
L
P
G
P
T
I
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789858
623
70278
V540
S
W
A
S
L
D
D
V
T
K
L
L
P
G
P
Poplar Tree
Populus trichocarpa
XP_002316387
596
67323
T513
L
P
G
P
H
S
E
T
K
R
G
G
F
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KJ7
592
66894
H509
L
K
L
L
P
G
P
H
L
E
T
K
R
S
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.4
97.5
N.A.
97.4
96.7
N.A.
30.6
81.6
N.A.
N.A.
N.A.
28
32
N.A.
46.7
Protein Similarity:
100
100
98.2
99
N.A.
98.8
98.2
N.A.
51.2
93.3
N.A.
N.A.
N.A.
50.4
54.1
N.A.
69.3
P-Site Identity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
0
86.6
N.A.
N.A.
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
6.6
93.3
N.A.
N.A.
N.A.
26.6
6.6
N.A.
13.3
Percent
Protein Identity:
29.5
N.A.
N.A.
29.3
N.A.
N.A.
Protein Similarity:
50
N.A.
N.A.
50.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
16
8
8
0
0
0
0
8
39
8
0
% D
% Glu:
47
0
0
8
31
0
16
8
0
8
0
0
24
47
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% F
% Gly:
0
8
8
0
0
16
0
8
8
16
54
8
0
8
16
% G
% His:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
0
% I
% Lys:
8
8
0
0
0
0
0
0
8
8
8
8
0
0
0
% K
% Leu:
24
0
16
54
8
0
16
8
8
8
16
54
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
8
8
0
8
8
8
8
8
0
8
8
8
% P
% Gln:
8
47
8
0
0
0
0
0
8
47
0
0
0
0
0
% Q
% Arg:
0
0
0
8
8
54
47
0
0
8
0
0
8
0
0
% R
% Ser:
8
8
0
8
8
8
8
39
0
0
0
0
0
24
16
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
16
8
0
0
0
% T
% Val:
0
8
47
8
0
0
0
8
8
0
0
0
0
8
54
% V
% Trp:
0
8
8
0
0
0
0
8
47
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _