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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS16
All Species:
22.42
Human Site:
S563
Identified Species:
49.33
UniProt:
Q9H269
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H269
NP_072097.2
839
94694
S563
K
R
S
K
L
A
L
S
K
A
I
E
S
G
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850284
839
94836
S563
K
R
S
K
L
A
L
S
K
A
I
E
S
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q4
839
94826
S563
K
R
S
K
L
A
L
S
K
A
I
E
S
G
D
Rat
Rattus norvegicus
NP_001005541
839
94889
S563
K
R
S
K
L
A
L
S
K
A
I
E
S
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424209
819
93397
S544
K
R
S
K
L
A
L
S
K
A
I
E
S
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001091659
835
94501
S560
K
K
S
P
L
A
L
S
K
A
I
E
S
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649877
833
95954
G561
R
K
F
D
R
A
V
G
S
A
T
Q
S
G
D
Honey Bee
Apis mellifera
XP_392642
835
95889
R562
G
E
E
K
A
A
L
R
K
A
V
E
S
G
N
Nematode Worm
Caenorhab. elegans
Q11182
852
95824
Q581
N
D
V
S
A
A
L
Q
K
A
S
A
S
Q
R
Sea Urchin
Strong. purpuratus
XP_001195237
597
67987
K374
P
L
T
Y
D
Q
L
K
K
L
T
L
T
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03308
798
92723
A541
L
T
I
S
L
L
I
A
L
S
K
K
L
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.8
N.A.
96.9
96.6
N.A.
N.A.
75.6
N.A.
67.5
N.A.
35.6
43.1
24.4
39.6
Protein Similarity:
100
N.A.
N.A.
99
N.A.
98.6
98.5
N.A.
N.A.
87.4
N.A.
83
N.A.
58.5
63.6
43.4
52.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
N.A.
86.6
N.A.
33.3
53.3
33.3
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
N.A.
93.3
N.A.
60
66.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
82
0
10
0
82
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
0
0
0
0
0
0
0
0
0
64
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
0
64
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
0
0
0
73
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
55
0
0
0
0
% I
% Lys:
55
19
0
55
0
0
0
10
82
0
10
10
0
0
0
% K
% Leu:
10
10
0
0
64
10
82
0
10
10
0
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% N
% Pro:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
10
0
0
0
10
0
10
0
% Q
% Arg:
10
46
0
0
10
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
0
0
55
19
0
0
0
55
10
10
10
0
82
0
0
% S
% Thr:
0
10
10
0
0
0
0
0
0
0
19
0
10
10
0
% T
% Val:
0
0
10
0
0
0
10
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _