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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS16 All Species: 13.64
Human Site: S631 Identified Species: 30
UniProt: Q9H269 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H269 NP_072097.2 839 94694 S631 D N H Q E L G S F H I R A S Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850284 839 94836 S631 D N H Q E L G S F H I R A S Y
Cat Felis silvestris
Mouse Mus musculus Q920Q4 839 94826 S631 D N H Q E L G S F H I R A S Y
Rat Rattus norvegicus NP_001005541 839 94889 S631 D N H Q E L G S F H I R A S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_424209 819 93397 N612 D N H Q E L G N F H V H S S Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001091659 835 94501 N628 D D H E E L G N F Y V K A S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649877 833 95954 E629 D D Q K A I A E Y H F Q N A I
Honey Bee Apis mellifera XP_392642 835 95889 I630 D D F H S Q A I W F I T E S Y
Nematode Worm Caenorhab. elegans Q11182 852 95824 D649 A L L E Q A S D F E R Q T L F
Sea Urchin Strong. purpuratus XP_001195237 597 67987 G440 Q S I K E K L G D T P G I A Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q03308 798 92723 L607 Q Q S L H S F L P Q I K D L Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.8 N.A. 96.9 96.6 N.A. N.A. 75.6 N.A. 67.5 N.A. 35.6 43.1 24.4 39.6
Protein Similarity: 100 N.A. N.A. 99 N.A. 98.6 98.5 N.A. N.A. 87.4 N.A. 83 N.A. 58.5 63.6 43.4 52.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. 73.3 N.A. 60 N.A. 13.3 26.6 6.6 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 100 N.A. 53.3 40 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 10 19 0 0 0 0 0 46 19 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 73 28 0 0 0 0 0 10 10 0 0 0 10 0 0 % D
% Glu: 0 0 0 19 64 0 0 10 0 10 0 0 10 0 0 % E
% Phe: 0 0 10 0 0 0 10 0 64 10 10 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 55 10 0 0 0 10 0 0 0 % G
% His: 0 0 55 10 10 0 0 0 0 55 0 10 0 0 0 % H
% Ile: 0 0 10 0 0 10 0 10 0 0 55 0 10 0 10 % I
% Lys: 0 0 0 19 0 10 0 0 0 0 0 19 0 0 0 % K
% Leu: 0 10 10 10 0 55 10 10 0 0 0 0 0 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 46 0 0 0 0 0 19 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % P
% Gln: 19 10 10 46 10 10 0 0 0 10 0 19 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 37 0 0 0 % R
% Ser: 0 10 10 0 10 10 10 37 0 0 0 0 10 64 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 10 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 82 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _