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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS16
All Species:
24.24
Human Site:
S695
Identified Species:
53.33
UniProt:
Q9H269
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H269
NP_072097.2
839
94694
S695
G
G
Q
F
L
D
L
S
L
H
D
T
V
T
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850284
839
94836
S695
G
G
H
F
V
D
L
S
L
H
D
T
V
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q4
839
94826
S695
G
G
R
F
L
D
L
S
L
H
D
T
V
T
T
Rat
Rattus norvegicus
NP_001005541
839
94889
S695
G
G
R
F
L
D
L
S
L
H
D
T
V
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424209
819
93397
S675
D
K
P
Y
L
D
L
S
L
H
N
T
V
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001091659
835
94501
S691
G
E
P
L
V
G
F
S
L
H
D
T
M
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649877
833
95954
S689
N
V
S
L
N
G
L
S
I
H
E
T
I
Q
E
Honey Bee
Apis mellifera
XP_392642
835
95889
P693
Q
E
I
I
V
G
K
P
L
H
D
T
V
K
I
Nematode Worm
Caenorhab. elegans
Q11182
852
95824
S712
Q
R
G
Q
A
D
M
S
V
R
D
T
V
I
E
Sea Urchin
Strong. purpuratus
XP_001195237
597
67987
I494
R
T
S
L
R
K
A
I
E
S
G
D
T
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03308
798
92723
G667
L
S
K
L
I
E
T
G
Q
D
K
Q
V
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.8
N.A.
96.9
96.6
N.A.
N.A.
75.6
N.A.
67.5
N.A.
35.6
43.1
24.4
39.6
Protein Similarity:
100
N.A.
N.A.
99
N.A.
98.6
98.5
N.A.
N.A.
87.4
N.A.
83
N.A.
58.5
63.6
43.4
52.9
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
93.3
93.3
N.A.
N.A.
60
N.A.
53.3
N.A.
26.6
33.3
33.3
0
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
N.A.
80
N.A.
66.6
N.A.
46.6
40
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
55
0
0
0
10
64
10
0
10
0
% D
% Glu:
0
19
0
0
0
10
0
0
10
0
10
0
0
0
28
% E
% Phe:
0
0
0
37
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
46
37
10
0
0
28
0
10
0
0
10
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
73
0
0
0
0
0
% H
% Ile:
0
0
10
10
10
0
0
10
10
0
0
0
10
10
10
% I
% Lys:
0
10
10
0
0
10
10
0
0
0
10
0
0
19
0
% K
% Leu:
10
0
0
37
37
0
55
0
64
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
19
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
19
0
10
10
0
0
0
0
10
0
0
10
0
10
0
% Q
% Arg:
10
10
19
0
10
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
10
19
0
0
0
0
73
0
10
0
0
0
10
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
0
82
10
46
55
% T
% Val:
0
10
0
0
28
0
0
0
10
0
0
0
73
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _