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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS16
All Species:
21.82
Human Site:
Y109
Identified Species:
48
UniProt:
Q9H269
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H269
NP_072097.2
839
94694
Y109
E
D
G
A
V
L
V
Y
G
L
H
G
D
F
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850284
839
94836
Y109
E
D
G
V
V
L
V
Y
G
L
H
G
D
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q4
839
94826
Y109
E
D
G
A
V
L
V
Y
G
L
H
G
D
F
R
Rat
Rattus norvegicus
NP_001005541
839
94889
Y109
E
D
G
A
V
L
V
Y
G
L
H
G
D
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424209
819
93397
F100
F
C
E
F
K
R
H
F
S
M
G
N
E
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001091659
835
94501
Y106
E
D
G
T
V
L
V
Y
D
L
L
G
G
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649877
833
95954
Y111
E
N
A
T
V
F
V
Y
D
M
F
G
R
E
K
Honey Bee
Apis mellifera
XP_392642
835
95889
Y110
D
D
G
M
I
H
I
Y
D
M
F
G
T
Y
L
Nematode Worm
Caenorhab. elegans
Q11182
852
95824
F115
K
A
G
R
A
H
I
F
S
S
L
G
E
K
I
Sea Urchin
Strong. purpuratus
XP_001195237
597
67987
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03308
798
92723
P106
P
L
T
I
E
S
V
P
L
Q
D
P
T
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.8
N.A.
96.9
96.6
N.A.
N.A.
75.6
N.A.
67.5
N.A.
35.6
43.1
24.4
39.6
Protein Similarity:
100
N.A.
N.A.
99
N.A.
98.6
98.5
N.A.
N.A.
87.4
N.A.
83
N.A.
58.5
63.6
43.4
52.9
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
N.A.
0
N.A.
66.6
N.A.
33.3
26.6
13.3
0
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
N.A.
20
N.A.
73.3
N.A.
53.3
60
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
28
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
55
0
0
0
0
0
0
28
0
10
0
37
0
10
% D
% Glu:
55
0
10
0
10
0
0
0
0
0
0
0
19
10
0
% E
% Phe:
10
0
0
10
0
10
0
19
0
0
19
0
0
46
0
% F
% Gly:
0
0
64
0
0
0
0
0
37
0
10
73
10
0
0
% G
% His:
0
0
0
0
0
19
10
0
0
0
37
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
19
0
0
0
0
0
0
10
10
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
19
% K
% Leu:
0
10
0
0
0
46
0
0
10
46
19
0
0
0
19
% L
% Met:
0
0
0
10
0
0
0
0
0
28
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
37
% R
% Ser:
0
0
0
0
0
10
0
0
19
10
0
0
0
0
0
% S
% Thr:
0
0
10
19
0
0
0
0
0
0
0
0
19
0
0
% T
% Val:
0
0
0
10
55
0
64
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _