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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS16
All Species:
23.94
Human Site:
Y638
Identified Species:
52.67
UniProt:
Q9H269
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H269
NP_072097.2
839
94694
Y638
S
F
H
I
R
A
S
Y
A
A
E
E
R
I
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850284
839
94836
Y638
S
F
H
I
R
A
S
Y
A
A
E
E
R
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q4
839
94826
Y638
S
F
H
I
R
A
S
Y
A
A
E
E
R
I
E
Rat
Rattus norvegicus
NP_001005541
839
94889
Y638
S
F
H
I
R
A
S
Y
A
A
E
E
R
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424209
819
93397
Y619
N
F
H
V
H
S
S
Y
S
E
K
R
I
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001091659
835
94501
Y635
N
F
Y
V
K
A
S
Y
K
E
Q
R
L
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649877
833
95954
I636
E
Y
H
F
Q
N
A
I
E
T
E
G
L
E
S
Honey Bee
Apis mellifera
XP_392642
835
95889
Y637
I
W
F
I
T
E
S
Y
Q
R
K
N
V
M
S
Nematode Worm
Caenorhab. elegans
Q11182
852
95824
F656
D
F
E
R
Q
T
L
F
H
F
D
V
A
E
T
Sea Urchin
Strong. purpuratus
XP_001195237
597
67987
Y447
G
D
T
P
G
I
A
Y
S
E
I
A
K
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03308
798
92723
Y614
L
P
Q
I
K
D
L
Y
S
Q
V
Q
N
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.8
N.A.
96.9
96.6
N.A.
N.A.
75.6
N.A.
67.5
N.A.
35.6
43.1
24.4
39.6
Protein Similarity:
100
N.A.
N.A.
99
N.A.
98.6
98.5
N.A.
N.A.
87.4
N.A.
83
N.A.
58.5
63.6
43.4
52.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
26.6
N.A.
26.6
N.A.
13.3
20
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
60
N.A.
60
N.A.
33.3
40
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
46
19
0
37
37
0
10
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
10
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
10
0
0
10
0
0
10
28
46
37
0
37
46
% E
% Phe:
0
64
10
10
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
55
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
55
0
10
0
10
0
0
10
0
10
37
0
% I
% Lys:
0
0
0
0
19
0
0
0
10
0
19
0
10
10
0
% K
% Leu:
10
0
0
0
0
0
19
0
0
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
19
0
0
0
0
10
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
19
0
0
0
10
10
10
10
0
0
0
% Q
% Arg:
0
0
0
10
37
0
0
0
0
10
0
19
37
0
0
% R
% Ser:
37
0
0
0
0
10
64
0
28
0
0
0
0
10
19
% S
% Thr:
0
0
10
0
10
10
0
0
0
10
0
0
0
0
10
% T
% Val:
0
0
0
19
0
0
0
0
0
0
10
10
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _