Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS11 All Species: 4.55
Human Site: S23 Identified Species: 7.69
UniProt: Q9H270 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H270 NP_068375.3 941 107837 S23 E L V K E P L S N D G A A P G
Chimpanzee Pan troglodytes XP_508805 941 107763 S23 E L V K E P L S N D G A A P G
Rhesus Macaque Macaca mulatta XP_001101032 941 107684 G23 E L V K E P L G N D G A A P G
Dog Lupus familis XP_546492 941 107605 G23 E L V K E P L G N D G A A P A
Cat Felis silvestris
Mouse Mus musculus Q91W86 941 107751 G23 E L V K E P L G N D G A A P G
Rat Rattus norvegicus NP_001101608 878 101153 A19 L Q L T G F Q A Y K L R V T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417847 929 106402 G23 E M V K E P P G P E G A G G K
Frog Xenopus laevis NP_001088406 914 104616 P21 E K E Q V R V P G E G G S L L
Zebra Danio Brachydanio rerio XP_002663611 927 106605 K19 F F D K E T V K D P S E N G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393972 1079 122741 G20 D L K K E V D G G K V A T A L
Nematode Worm Caenorhab. elegans Q09600 980 111990 D19 F D R S V V F D K D D P K Q K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321189 962 108854 I20 K Y G G K S S I P E D V T A G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_027676 932 105695 P19 E K Y G G K I P E D V T G D I
Baker's Yeast Sacchar. cerevisiae P12868 1029 117459 N21 N I P I R D P N F G G D S L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.2 98 N.A. 97.9 91.5 N.A. N.A. 83.5 77.4 74.1 N.A. N.A. 41.3 26.4 N.A.
Protein Similarity: 100 99.8 99.5 98.9 N.A. 98.9 92.4 N.A. N.A. 91.5 86.7 85.2 N.A. N.A. 58.2 46.9 N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 0 N.A. N.A. 46.6 13.3 13.3 N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: 100 100 93.3 86.6 N.A. 93.3 13.3 N.A. N.A. 60 40 26.6 N.A. N.A. 33.3 6.6 N.A.
Percent
Protein Identity: 38.4 N.A. N.A. 40.8 20.8 N.A.
Protein Similarity: 57.3 N.A. N.A. 60.8 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 50 36 15 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 0 8 8 8 8 50 15 8 0 8 0 % D
% Glu: 58 0 8 0 58 0 0 0 8 22 0 8 0 0 0 % E
% Phe: 15 8 0 0 0 8 8 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 8 15 15 0 0 36 15 8 58 8 15 15 36 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 8 0 8 0 0 8 8 0 0 0 0 0 0 8 % I
% Lys: 8 15 8 58 8 8 0 8 8 15 0 0 8 0 22 % K
% Leu: 8 43 8 0 0 0 36 0 0 0 8 0 0 15 22 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 36 0 0 0 8 0 0 % N
% Pro: 0 0 8 0 0 43 15 15 15 8 0 8 0 36 0 % P
% Gln: 0 8 0 8 0 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 8 8 0 0 0 0 0 8 0 0 0 % R
% Ser: 0 0 0 8 0 8 8 15 0 0 8 0 15 0 0 % S
% Thr: 0 0 0 8 0 8 0 0 0 0 0 8 15 8 0 % T
% Val: 0 0 43 0 15 15 15 0 0 0 15 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _