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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS11
All Species:
26.67
Human Site:
S296
Identified Species:
45.13
UniProt:
Q9H270
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H270
NP_068375.3
941
107837
S296
D
R
K
V
S
P
K
S
E
F
T
S
R
D
S
Chimpanzee
Pan troglodytes
XP_508805
941
107763
S296
D
R
K
V
S
P
K
S
E
F
T
S
R
D
S
Rhesus Macaque
Macaca mulatta
XP_001101032
941
107684
S296
D
R
K
V
S
P
K
S
E
F
T
S
R
D
S
Dog
Lupus familis
XP_546492
941
107605
S296
D
R
K
V
S
P
K
S
E
F
T
S
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91W86
941
107751
S296
D
R
K
V
S
P
K
S
E
F
T
S
R
D
S
Rat
Rattus norvegicus
NP_001101608
878
101153
L271
F
E
D
V
V
D
V
L
A
E
W
G
S
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417847
929
106402
S285
D
R
K
T
S
P
K
S
E
F
A
G
N
E
A
Frog
Xenopus laevis
NP_001088406
914
104616
F278
V
S
S
D
R
L
P
F
A
G
R
A
G
D
C
Zebra Danio
Brachydanio rerio
XP_002663611
927
106605
S281
S
N
K
S
P
S
K
S
D
Y
G
S
R
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393972
1079
122741
T282
A
A
N
V
P
R
T
T
T
T
I
S
P
I
P
Nematode Worm
Caenorhab. elegans
Q09600
980
111990
H292
L
A
L
L
T
K
H
H
S
L
I
Q
K
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321189
962
108854
Y279
F
L
G
W
F
R
G
Y
L
L
C
V
I
A
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_027676
932
105695
Y270
F
M
G
W
F
R
G
Y
L
L
C
V
I
D
D
Baker's Yeast
Sacchar. cerevisiae
P12868
1029
117459
S287
E
T
G
V
P
T
T
S
I
S
V
N
E
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
98
N.A.
97.9
91.5
N.A.
N.A.
83.5
77.4
74.1
N.A.
N.A.
41.3
26.4
N.A.
Protein Similarity:
100
99.8
99.5
98.9
N.A.
98.9
92.4
N.A.
N.A.
91.5
86.7
85.2
N.A.
N.A.
58.2
46.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
60
6.6
33.3
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
73.3
13.3
53.3
N.A.
N.A.
20
26.6
N.A.
Percent
Protein Identity:
38.4
N.A.
N.A.
40.8
20.8
N.A.
Protein Similarity:
57.3
N.A.
N.A.
60.8
39.4
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
0
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
0
0
0
0
15
0
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
8
% C
% Asp:
43
0
8
8
0
8
0
0
8
0
0
0
0
50
15
% D
% Glu:
8
8
0
0
0
0
0
0
43
8
0
0
8
15
0
% E
% Phe:
22
0
0
0
15
0
0
8
0
43
0
0
0
0
0
% F
% Gly:
0
0
22
0
0
0
15
0
0
8
8
15
8
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
15
0
15
8
0
% I
% Lys:
0
0
50
0
0
8
50
0
0
0
0
0
8
0
0
% K
% Leu:
8
8
8
8
0
8
0
8
15
22
0
0
0
15
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
22
43
8
0
0
0
0
0
8
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
0
43
0
0
8
22
0
0
0
0
8
0
43
0
8
% R
% Ser:
8
8
8
8
43
8
0
58
8
8
0
50
8
0
43
% S
% Thr:
0
8
0
8
8
8
15
8
8
8
36
0
0
0
8
% T
% Val:
8
0
0
58
8
0
8
0
0
0
8
15
0
0
0
% V
% Trp:
0
0
0
15
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _