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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS11 All Species: 16.97
Human Site: S480 Identified Species: 28.72
UniProt: Q9H270 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H270 NP_068375.3 941 107837 S480 F I K K K S E S E V H F D V E
Chimpanzee Pan troglodytes XP_508805 941 107763 S480 F I K T K S E S E V H F D V E
Rhesus Macaque Macaca mulatta XP_001101032 941 107684 S480 F I K T K S E S E V H F D V E
Dog Lupus familis XP_546492 941 107605 S480 F I K T K S E S E V H F D V E
Cat Felis silvestris
Mouse Mus musculus Q91W86 941 107751 S480 F I K T K S E S E V H F D V E
Rat Rattus norvegicus NP_001101608 878 101153 E450 A E N H A H H E W Y L K I Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417847 929 106402 E469 F I K A S E S E V R F D V E T
Frog Xenopus laevis NP_001088406 914 104616 E462 F I K A S E G E V H F D V E I
Zebra Danio Brachydanio rerio XP_002663611 927 106605 E465 F I K S N E S E V H F D V E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393972 1079 122741 E466 F I M T K D R E V D F D V E I
Nematode Worm Caenorhab. elegans Q09600 980 111990 G476 F V N K I T D G T R V S R M R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321189 962 108854 A463 F I K S E D G A G E H K F D V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_027676 932 105695 I454 F I R K E D G I G E L K F D V
Baker's Yeast Sacchar. cerevisiae P12868 1029 117459 K480 F I Q H F D R K G I W N E G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.2 98 N.A. 97.9 91.5 N.A. N.A. 83.5 77.4 74.1 N.A. N.A. 41.3 26.4 N.A.
Protein Similarity: 100 99.8 99.5 98.9 N.A. 98.9 92.4 N.A. N.A. 91.5 86.7 85.2 N.A. N.A. 58.2 46.9 N.A.
P-Site Identity: 100 93.3 93.3 93.3 N.A. 93.3 0 N.A. N.A. 20 20 20 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 0 N.A. N.A. 20 20 20 N.A. N.A. 20 40 N.A.
Percent
Protein Identity: 38.4 N.A. N.A. 40.8 20.8 N.A.
Protein Similarity: 57.3 N.A. N.A. 60.8 39.4 N.A.
P-Site Identity: 26.6 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 40 N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 8 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 29 8 0 0 8 0 29 36 15 0 % D
% Glu: 0 8 0 0 15 22 36 36 36 15 0 0 8 29 36 % E
% Phe: 93 0 0 0 8 0 0 0 0 0 29 36 15 0 0 % F
% Gly: 0 0 0 0 0 0 22 8 22 0 0 0 0 8 0 % G
% His: 0 0 0 15 0 8 8 0 0 15 43 0 0 0 0 % H
% Ile: 0 86 0 0 8 0 0 8 0 8 0 0 8 0 22 % I
% Lys: 0 0 65 22 43 0 0 8 0 0 0 22 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 15 0 8 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 15 0 0 15 0 0 8 0 8 % R
% Ser: 0 0 0 15 15 36 15 36 0 0 0 8 0 0 0 % S
% Thr: 0 0 0 36 0 8 0 0 8 0 0 0 0 0 8 % T
% Val: 0 8 0 0 0 0 0 0 29 36 8 0 29 36 22 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _