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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS11
All Species:
17.27
Human Site:
S574
Identified Species:
29.23
UniProt:
Q9H270
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H270
NP_068375.3
941
107837
S574
L
C
T
D
Y
R
P
S
L
E
G
R
S
D
R
Chimpanzee
Pan troglodytes
XP_508805
941
107763
S574
L
C
T
D
Y
R
P
S
L
E
G
R
S
D
R
Rhesus Macaque
Macaca mulatta
XP_001101032
941
107684
S574
L
C
T
D
Y
R
P
S
L
E
G
H
S
D
R
Dog
Lupus familis
XP_546492
941
107605
S574
L
C
T
D
Y
Q
P
S
L
E
G
R
G
D
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91W86
941
107751
S574
L
C
T
D
Y
R
P
S
L
E
G
R
G
D
R
Rat
Rattus norvegicus
NP_001101608
878
101153
F544
N
P
R
E
L
K
A
F
L
E
H
M
S
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417847
929
106402
G563
C
T
D
Y
Q
P
T
G
D
S
E
G
P
G
I
Frog
Xenopus laevis
NP_001088406
914
104616
G556
C
T
S
F
P
Q
N
G
E
G
S
R
A
N
P
Zebra Danio
Brachydanio rerio
XP_002663611
927
106605
K559
C
T
D
Y
H
P
S
K
D
S
T
D
R
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393972
1079
122741
K560
T
N
Y
R
P
S
N
K
P
L
V
D
Q
E
T
Nematode Worm
Caenorhab. elegans
Q09600
980
111990
A570
K
I
Q
E
N
T
D
A
K
K
N
N
F
M
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321189
962
108854
E557
R
L
C
T
E
D
G
E
S
T
K
R
E
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_027676
932
105695
I548
R
L
C
T
E
Q
G
I
P
N
G
V
F
L
S
Baker's Yeast
Sacchar. cerevisiae
P12868
1029
117459
L574
L
V
T
Y
S
K
K
L
L
E
E
S
P
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
98
N.A.
97.9
91.5
N.A.
N.A.
83.5
77.4
74.1
N.A.
N.A.
41.3
26.4
N.A.
Protein Similarity:
100
99.8
99.5
98.9
N.A.
98.9
92.4
N.A.
N.A.
91.5
86.7
85.2
N.A.
N.A.
58.2
46.9
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
20
N.A.
N.A.
0
6.6
6.6
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
40
N.A.
N.A.
0
33.3
13.3
N.A.
N.A.
6.6
26.6
N.A.
Percent
Protein Identity:
38.4
N.A.
N.A.
40.8
20.8
N.A.
Protein Similarity:
57.3
N.A.
N.A.
60.8
39.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% A
% Cys:
22
36
15
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
36
0
8
8
0
15
0
0
15
0
43
0
% D
% Glu:
0
0
0
15
15
0
0
8
8
50
15
0
8
15
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
15
15
0
8
43
8
15
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
15
8
15
8
8
8
0
0
0
0
% K
% Leu:
43
15
0
0
8
0
0
8
50
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
8
8
0
0
8
0
15
0
0
8
8
8
0
15
0
% N
% Pro:
0
8
0
0
15
15
36
0
15
0
0
0
15
0
8
% P
% Gln:
0
0
8
0
8
22
0
0
0
0
0
0
8
0
0
% Q
% Arg:
15
0
8
8
0
29
0
0
0
0
0
43
8
0
43
% R
% Ser:
0
0
8
0
8
8
8
36
8
15
8
8
29
8
22
% S
% Thr:
8
22
43
15
0
8
8
0
0
8
8
0
0
0
8
% T
% Val:
0
8
0
0
0
0
0
0
0
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
22
36
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _