KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS11
All Species:
19.09
Human Site:
S590
Identified Species:
32.31
UniProt:
Q9H270
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H270
NP_068375.3
941
107837
S590
A
P
G
C
R
A
N
S
E
E
F
I
P
I
F
Chimpanzee
Pan troglodytes
XP_508805
941
107763
S590
A
P
G
C
R
A
N
S
E
E
F
I
P
I
F
Rhesus Macaque
Macaca mulatta
XP_001101032
941
107684
S590
A
P
G
C
R
A
N
S
E
E
F
I
P
I
F
Dog
Lupus familis
XP_546492
941
107605
S590
A
P
G
C
R
A
N
S
E
E
F
I
P
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q91W86
941
107751
S590
A
P
S
C
R
A
N
S
E
E
F
I
P
I
F
Rat
Rattus norvegicus
NP_001101608
878
101153
Y560
P
D
S
P
Q
G
I
Y
D
T
L
L
E
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417847
929
106402
E579
E
G
K
K
A
N
S
E
E
F
I
P
V
F
A
Frog
Xenopus laevis
NP_001088406
914
104616
N572
E
F
I
P
I
F
A
N
N
P
S
E
L
K
T
Zebra Danio
Brachydanio rerio
XP_002663611
927
106605
A575
D
R
P
V
E
N
K
A
N
P
E
E
F
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393972
1079
122741
V576
Y
G
N
I
C
Q
D
V
D
K
A
N
P
E
D
Nematode Worm
Caenorhab. elegans
Q09600
980
111990
M586
F
D
I
F
M
G
D
M
D
A
S
R
V
F
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321189
962
108854
P573
S
T
Y
L
T
M
L
P
S
P
V
D
F
L
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_027676
932
105695
I564
L
P
S
P
V
D
F
I
T
V
F
V
Q
H
P
Baker's Yeast
Sacchar. cerevisiae
P12868
1029
117459
F590
N
A
L
L
I
E
V
F
T
G
K
F
K
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
98
N.A.
97.9
91.5
N.A.
N.A.
83.5
77.4
74.1
N.A.
N.A.
41.3
26.4
N.A.
Protein Similarity:
100
99.8
99.5
98.9
N.A.
98.9
92.4
N.A.
N.A.
91.5
86.7
85.2
N.A.
N.A.
58.2
46.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
N.A.
6.6
0
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
N.A.
13.3
6.6
13.3
N.A.
N.A.
26.6
13.3
N.A.
Percent
Protein Identity:
38.4
N.A.
N.A.
40.8
20.8
N.A.
Protein Similarity:
57.3
N.A.
N.A.
60.8
39.4
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
8
0
0
8
36
8
8
0
8
8
0
0
0
8
% A
% Cys:
0
0
0
36
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
0
8
15
0
22
0
0
8
0
0
8
% D
% Glu:
15
0
0
0
8
8
0
8
43
36
8
15
8
8
0
% E
% Phe:
8
8
0
8
0
8
8
8
0
8
43
8
15
15
36
% F
% Gly:
0
15
29
0
0
15
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
15
8
15
0
8
8
0
0
8
36
0
43
0
% I
% Lys:
0
0
8
8
0
0
8
0
0
8
8
0
8
8
0
% K
% Leu:
8
0
8
15
0
0
8
0
0
0
8
8
8
15
8
% L
% Met:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
15
36
8
15
0
0
8
0
0
8
% N
% Pro:
8
43
8
22
0
0
0
8
0
22
0
8
43
8
15
% P
% Gln:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
36
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
8
0
22
0
0
0
8
36
8
0
15
0
0
0
8
% S
% Thr:
0
8
0
0
8
0
0
0
15
8
0
0
0
0
8
% T
% Val:
0
0
0
8
8
0
8
8
0
8
8
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _