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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS11
All Species:
31.21
Human Site:
Y341
Identified Species:
52.82
UniProt:
Q9H270
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H270
NP_068375.3
941
107837
Y341
L
A
E
W
G
S
L
Y
V
L
T
R
D
G
R
Chimpanzee
Pan troglodytes
XP_508805
941
107763
Y341
L
A
E
W
G
S
L
Y
V
L
T
R
D
G
R
Rhesus Macaque
Macaca mulatta
XP_001101032
941
107684
Y341
L
A
E
W
G
S
L
Y
V
L
T
R
D
G
R
Dog
Lupus familis
XP_546492
941
107605
Y341
L
A
E
W
G
S
L
Y
V
L
T
R
D
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91W86
941
107751
Y341
L
A
E
W
G
S
L
Y
V
L
T
R
D
G
R
Rat
Rattus norvegicus
NP_001101608
878
101153
S316
M
A
I
N
L
A
K
S
Q
H
L
D
S
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417847
929
106402
Y330
L
A
E
W
G
S
L
Y
V
L
T
R
D
G
K
Frog
Xenopus laevis
NP_001088406
914
104616
Y323
L
A
E
W
G
S
L
Y
V
L
T
R
D
G
L
Zebra Danio
Brachydanio rerio
XP_002663611
927
106605
Y326
L
A
E
W
G
S
F
Y
V
L
T
S
D
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393972
1079
122741
F327
L
S
E
W
G
G
F
F
I
L
S
G
D
N
K
Nematode Worm
Caenorhab. elegans
Q09600
980
111990
L337
F
I
A
G
S
T
M
L
V
L
S
H
D
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321189
962
108854
I324
L
C
E
W
G
N
I
I
L
I
M
T
D
K
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_027676
932
105695
I315
L
C
E
W
G
N
I
I
L
I
K
A
D
K
S
Baker's Yeast
Sacchar. cerevisiae
P12868
1029
117459
K332
F
S
T
S
Q
S
G
K
N
I
T
Y
L
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
98
N.A.
97.9
91.5
N.A.
N.A.
83.5
77.4
74.1
N.A.
N.A.
41.3
26.4
N.A.
Protein Similarity:
100
99.8
99.5
98.9
N.A.
98.9
92.4
N.A.
N.A.
91.5
86.7
85.2
N.A.
N.A.
58.2
46.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
93.3
93.3
73.3
N.A.
N.A.
40
26.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
100
93.3
73.3
N.A.
N.A.
73.3
46.6
N.A.
Percent
Protein Identity:
38.4
N.A.
N.A.
40.8
20.8
N.A.
Protein Similarity:
57.3
N.A.
N.A.
60.8
39.4
N.A.
P-Site Identity:
33.3
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
65
8
0
0
8
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
86
8
0
% D
% Glu:
0
0
79
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
15
0
0
0
0
0
15
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
79
8
8
0
0
0
0
8
0
58
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
8
8
0
0
0
15
15
8
22
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
8
0
0
8
0
0
15
15
% K
% Leu:
79
0
0
0
8
0
50
8
15
72
8
0
8
8
15
% L
% Met:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
15
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
50
0
8
36
% R
% Ser:
0
15
0
8
8
65
0
8
0
0
15
8
8
0
15
% S
% Thr:
0
0
8
0
0
8
0
0
0
0
65
8
0
0
15
% T
% Val:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% V
% Trp:
0
0
0
79
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _