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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS11
All Species:
18.18
Human Site:
Y91
Identified Species:
30.77
UniProt:
Q9H270
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H270
NP_068375.3
941
107837
Y91
K
L
R
V
T
H
L
Y
Q
L
K
Q
H
N
I
Chimpanzee
Pan troglodytes
XP_508805
941
107763
Y91
K
L
R
V
T
H
L
Y
Q
L
K
Q
H
N
I
Rhesus Macaque
Macaca mulatta
XP_001101032
941
107684
Y91
K
L
R
V
T
H
L
Y
Q
L
K
Q
H
N
I
Dog
Lupus familis
XP_546492
941
107605
Y91
K
L
R
V
T
H
L
Y
Q
L
K
Q
H
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91W86
941
107751
Y91
K
L
R
V
T
H
L
Y
Q
L
K
Q
H
N
I
Rat
Rattus norvegicus
NP_001101608
878
101153
H86
V
V
S
C
L
T
V
H
E
N
L
N
F
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417847
929
106402
E93
S
I
L
V
S
V
G
E
D
E
E
G
I
N
P
Frog
Xenopus laevis
NP_001088406
914
104616
E89
N
I
L
V
S
V
G
E
D
E
E
G
I
N
P
Zebra Danio
Brachydanio rerio
XP_002663611
927
106605
Q89
N
I
L
V
S
V
G
Q
D
E
P
G
I
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393972
1079
122741
D88
F
L
F
T
I
G
E
D
E
P
G
C
N
P
T
Nematode Worm
Caenorhab. elegans
Q09600
980
111990
E88
K
Y
L
F
S
I
G
E
D
D
E
T
V
N
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321189
962
108854
E87
L
V
T
V
G
E
D
E
Q
I
S
P
Q
Q
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_027676
932
105695
I86
T
V
G
E
D
E
Q
I
S
P
Q
Q
S
G
M
Baker's Yeast
Sacchar. cerevisiae
P12868
1029
117459
A92
G
E
F
L
V
A
L
A
E
S
I
G
K
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
98
N.A.
97.9
91.5
N.A.
N.A.
83.5
77.4
74.1
N.A.
N.A.
41.3
26.4
N.A.
Protein Similarity:
100
99.8
99.5
98.9
N.A.
98.9
92.4
N.A.
N.A.
91.5
86.7
85.2
N.A.
N.A.
58.2
46.9
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
13.3
13.3
13.3
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
33.3
33.3
26.6
N.A.
N.A.
20
26.6
N.A.
Percent
Protein Identity:
38.4
N.A.
N.A.
40.8
20.8
N.A.
Protein Similarity:
57.3
N.A.
N.A.
60.8
39.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
8
29
8
0
0
0
0
0
% D
% Glu:
0
8
0
8
0
15
8
29
22
22
22
0
0
0
0
% E
% Phe:
8
0
15
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
0
8
8
29
0
0
0
8
29
0
8
0
% G
% His:
0
0
0
0
0
36
0
8
0
0
0
0
36
0
0
% H
% Ile:
0
22
0
0
8
8
0
8
0
8
8
0
22
0
36
% I
% Lys:
43
0
0
0
0
0
0
0
0
0
36
0
8
0
0
% K
% Leu:
8
43
29
8
8
0
43
0
0
36
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
15
0
0
0
0
0
0
0
0
8
0
8
8
65
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
15
8
8
0
15
22
% P
% Gln:
0
0
0
0
0
0
8
8
43
0
8
43
8
8
0
% Q
% Arg:
0
0
36
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
29
0
0
0
8
8
8
0
8
0
15
% S
% Thr:
8
0
8
8
36
8
0
0
0
0
0
8
0
0
15
% T
% Val:
8
22
0
65
8
22
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _