KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT4
All Species:
30
Human Site:
S135
Identified Species:
55
UniProt:
Q9H2B2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2B2
NP_065834.1
425
47958
S135
E
G
E
K
E
S
V
S
P
E
S
L
K
S
S
Chimpanzee
Pan troglodytes
XP_523915
427
48140
S135
E
G
E
K
E
S
V
S
P
E
S
L
K
S
S
Rhesus Macaque
Macaca mulatta
XP_001083607
425
47898
S135
E
G
E
K
E
A
V
S
P
D
S
L
K
S
S
Dog
Lupus familis
XP_547596
425
48163
S135
E
G
E
K
E
A
V
S
P
D
S
L
K
S
S
Cat
Felis silvestris
Mouse
Mus musculus
P40749
425
47640
S135
E
T
E
K
E
A
N
S
P
E
S
L
K
S
S
Rat
Rattus norvegicus
P50232
425
47666
S135
E
T
E
K
E
A
V
S
P
E
S
L
K
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506963
425
47967
S135
E
S
E
K
D
S
I
S
L
D
S
L
K
S
N
Chicken
Gallus gallus
P47191
424
47487
A126
Q
A
L
K
D
D
D
A
E
T
G
L
T
D
G
Frog
Xenopus laevis
NP_001086261
424
47737
S134
E
K
D
K
D
S
I
S
P
E
S
V
K
S
S
Zebra Danio
Brachydanio rerio
NP_956242
439
48646
V148
A
G
T
P
E
S
V
V
S
S
H
T
P
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
E174
K
V
Q
P
D
M
E
E
L
T
E
N
A
E
E
Honey Bee
Apis mellifera
XP_393448
447
49774
N151
D
K
A
E
I
E
N
N
E
K
T
E
R
E
K
Nematode Worm
Caenorhab. elegans
P34693
441
49885
G141
A
Q
D
L
E
E
L
G
D
A
M
E
Q
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.8
95.2
N.A.
89.8
89.8
N.A.
91.5
30.8
82.8
65.3
N.A.
33.1
38.9
31.9
N.A.
Protein Similarity:
100
99.5
99.7
97.8
N.A.
94.5
94.8
N.A.
95.7
50.3
92.4
78.8
N.A.
48.7
59.7
49.6
N.A.
P-Site Identity:
100
100
86.6
86.6
N.A.
80
86.6
N.A.
60
13.3
66.6
26.6
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
86.6
33.3
93.3
33.3
N.A.
20
40
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
0
31
0
8
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
31
8
8
0
8
24
0
0
0
8
0
% D
% Glu:
62
0
54
8
62
16
8
8
16
39
8
16
0
16
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
39
0
0
0
0
0
8
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
16
0
0
0
0
0
0
0
0
% I
% Lys:
8
16
0
70
0
0
0
0
0
8
0
0
62
0
8
% K
% Leu:
0
0
8
8
0
0
8
0
16
0
0
62
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
16
8
0
0
0
8
0
8
8
% N
% Pro:
0
0
0
16
0
0
0
0
54
0
0
0
8
0
8
% P
% Gln:
8
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
0
0
39
0
62
8
8
62
0
0
62
54
% S
% Thr:
0
16
8
0
0
0
0
0
0
16
8
8
8
8
0
% T
% Val:
0
8
0
0
0
0
47
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _