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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHX5
All Species:
22.42
Human Site:
T178
Identified Species:
41.11
UniProt:
Q9H2C1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2C1
NP_071758.1
402
44406
T178
N
E
E
Q
N
S
G
T
K
R
R
G
P
R
T
Chimpanzee
Pan troglodytes
Q5IS44
406
44776
G177
E
N
D
D
Q
N
L
G
A
K
R
R
G
P
R
Rhesus Macaque
Macaca mulatta
XP_001111705
402
44357
T178
N
E
E
Q
N
S
G
T
K
R
R
G
P
R
T
Dog
Lupus familis
XP_543409
451
49581
T227
N
E
E
Q
N
S
G
T
K
R
R
G
P
R
T
Cat
Felis silvestris
Mouse
Mus musculus
P53776
390
43059
A155
K
Q
N
D
D
S
E
A
G
A
K
R
P
R
T
Rat
Rattus norvegicus
P61376
402
44369
T178
N
E
E
Q
N
S
G
T
K
R
R
G
P
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517055
231
26095
A19
G
T
K
C
A
G
C
A
Q
G
I
S
P
S
D
Chicken
Gallus gallus
P53411
406
44827
G177
E
N
D
D
Q
N
L
G
A
K
R
R
G
P
R
Frog
Xenopus laevis
P37137
402
44941
T178
N
E
E
Q
N
S
G
T
K
R
R
G
P
R
T
Zebra Danio
Brachydanio rerio
P52889
399
44494
T178
N
E
E
Q
N
S
C
T
K
R
R
G
P
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572505
505
54770
D200
G
G
P
L
G
T
S
D
I
S
V
Q
S
M
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P20154
405
45759
C178
M
E
G
N
R
F
V
C
Q
S
D
F
Q
T
A
Sea Urchin
Strong. purpuratus
NP_999810
480
53702
L178
S
D
A
I
S
P
S
L
G
V
T
P
A
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.8
99.7
87.3
N.A.
27.8
98.7
N.A.
55.2
73.8
85.3
79
N.A.
41.7
N.A.
40.9
54.1
Protein Similarity:
100
84.4
99.7
87.8
N.A.
46
98.7
N.A.
56.2
84.2
91.5
86.8
N.A.
52.8
N.A.
54.8
62.9
P-Site Identity:
100
6.6
100
100
N.A.
26.6
100
N.A.
6.6
6.6
100
93.3
N.A.
0
N.A.
6.6
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
46.6
100
N.A.
20
26.6
100
93.3
N.A.
13.3
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
16
16
8
0
0
8
0
8
% A
% Cys:
0
0
0
8
0
0
16
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
24
8
0
0
8
0
0
8
0
0
0
8
% D
% Glu:
16
54
47
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
16
8
8
0
8
8
39
16
16
8
0
47
16
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
47
16
8
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
16
8
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
47
16
8
8
47
16
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
8
0
0
0
0
0
8
62
16
0
% P
% Gln:
0
8
0
47
16
0
0
0
16
0
0
8
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
47
62
24
0
54
16
% R
% Ser:
8
0
0
0
8
54
16
0
0
16
0
8
8
8
8
% S
% Thr:
0
8
0
0
0
8
0
47
0
0
8
0
0
16
62
% T
% Val:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _