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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEMA6A All Species: 14.85
Human Site: S714 Identified Species: 32.67
UniProt: Q9H2E6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2E6 NP_065847.1 1030 114369 S714 G L F G D T Q S K D P K P E A
Chimpanzee Pan troglodytes XP_001150971 1030 114440 S714 G L F G D T Q S K D P K P E A
Rhesus Macaque Macaca mulatta XP_001112236 1073 119718 Q730 S P V K E Y Q Q N I D S P K L
Dog Lupus familis XP_858843 1030 114125 S714 G L F G D T Q S K D P K P E A
Cat Felis silvestris
Mouse Mus musculus O35464 1031 114414 S714 G L F G D T Q S K D P K P E A
Rat Rattus norvegicus O70141 887 95734 S573 E Q D V S G A S T S G L G D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513097 932 103818 P618 G S S D G T D P F R A V S S H
Chicken Gallus gallus Q90607 772 88849 V458 I G T D I G T V L K V V S I P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q9W686 778 88886 S464 G T V L K V V S I P R G T W H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24322 850 95478 E535 H G A P R W L E E N Y F Y Q N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17330 712 78063 R398 L H H P L L H R P I P S V A A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 46.8 95.6 N.A. 94.9 42 N.A. 83.5 26.7 N.A. 26.3 N.A. 28.7 N.A. 25.1 N.A.
Protein Similarity: 100 99.7 62.8 97.7 N.A. 97.3 56.4 N.A. 86.9 41.8 N.A. 40.8 N.A. 45.4 N.A. 40.1 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 100 6.6 N.A. 13.3 0 N.A. 13.3 N.A. 0 N.A. 13.3 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 13.3 N.A. 13.3 0 N.A. 13.3 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 0 0 0 10 0 0 10 46 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 10 19 37 0 10 0 0 37 10 0 0 10 0 % D
% Glu: 10 0 0 0 10 0 0 10 10 0 0 0 0 37 0 % E
% Phe: 0 0 37 0 0 0 0 0 10 0 0 10 0 0 0 % F
% Gly: 55 19 0 37 10 19 0 0 0 0 10 10 10 0 0 % G
% His: 10 10 10 0 0 0 10 0 0 0 0 0 0 0 19 % H
% Ile: 10 0 0 0 10 0 0 0 10 19 0 0 0 10 0 % I
% Lys: 0 0 0 10 10 0 0 0 37 10 0 37 0 10 0 % K
% Leu: 10 37 0 10 10 10 10 0 10 0 0 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 10 % N
% Pro: 0 10 0 19 0 0 0 10 10 10 46 0 46 0 10 % P
% Gln: 0 10 0 0 0 0 46 10 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 10 0 0 10 0 10 10 0 0 0 0 % R
% Ser: 10 10 10 0 10 0 0 55 0 10 0 19 19 10 0 % S
% Thr: 0 10 10 0 0 46 10 0 10 0 0 0 10 0 0 % T
% Val: 0 0 19 10 0 10 10 10 0 0 10 19 10 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 10 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _