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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA6A
All Species:
8.79
Human Site:
S863
Identified Species:
19.33
UniProt:
Q9H2E6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2E6
NP_065847.1
1030
114369
S863
K
E
H
L
S
S
K
S
P
N
H
G
V
N
L
Chimpanzee
Pan troglodytes
XP_001150971
1030
114440
S863
K
E
H
L
S
S
K
S
P
N
H
G
V
N
L
Rhesus Macaque
Macaca mulatta
XP_001112236
1073
119718
L879
S
V
D
S
R
N
T
L
N
D
L
L
K
H
L
Dog
Lupus familis
XP_858843
1030
114125
S863
K
E
H
L
S
S
K
S
P
N
H
G
V
T
L
Cat
Felis silvestris
Mouse
Mus musculus
O35464
1031
114414
K863
I
K
E
H
L
S
S
K
S
P
N
H
G
V
N
Rat
Rattus norvegicus
O70141
887
95734
P722
P
L
P
Q
K
R
L
P
T
T
H
P
H
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513097
932
103818
K767
S
T
P
T
L
Q
Q
K
R
K
P
S
R
G
S
Chicken
Gallus gallus
Q90607
772
88849
V607
P
K
S
Q
R
A
I
V
Y
W
Q
F
Q
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q9W686
778
88886
F613
R
A
L
I
Y
W
Q
F
Q
R
H
G
E
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
E684
V
E
E
V
T
Y
A
E
P
V
L
L
P
Q
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17330
712
78063
P547
F
G
Q
S
E
Q
C
P
E
G
I
I
V
R
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
46.8
95.6
N.A.
94.9
42
N.A.
83.5
26.7
N.A.
26.3
N.A.
28.7
N.A.
25.1
N.A.
Protein Similarity:
100
99.7
62.8
97.7
N.A.
97.3
56.4
N.A.
86.9
41.8
N.A.
40.8
N.A.
45.4
N.A.
40.1
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
6.6
6.6
N.A.
0
0
N.A.
13.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
20
6.6
N.A.
6.6
13.3
N.A.
40
N.A.
26.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
0
% D
% Glu:
0
37
19
0
10
0
0
10
10
0
0
0
10
0
10
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
10
0
37
10
10
0
% G
% His:
0
0
28
10
0
0
0
0
0
0
46
10
10
10
19
% H
% Ile:
10
0
0
10
0
0
10
0
0
0
10
10
0
0
0
% I
% Lys:
28
19
0
0
10
0
28
19
0
10
0
0
10
10
0
% K
% Leu:
0
10
10
28
19
0
10
10
0
0
19
19
0
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
28
10
0
0
19
10
% N
% Pro:
19
0
19
0
0
0
0
19
37
10
10
10
10
0
10
% P
% Gln:
0
0
10
19
0
19
19
0
10
0
10
0
10
10
10
% Q
% Arg:
10
0
0
0
19
10
0
0
10
10
0
0
10
10
0
% R
% Ser:
19
0
10
19
28
37
10
28
10
0
0
10
0
0
10
% S
% Thr:
0
10
0
10
10
0
10
0
10
10
0
0
0
10
0
% T
% Val:
10
10
0
10
0
0
0
10
0
10
0
0
37
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _