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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPC1
All Species:
17.88
Human Site:
S515
Identified Species:
35.76
UniProt:
Q9H2F5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2F5
NP_079485.1
836
93463
S515
K
S
F
S
K
D
L
S
Q
I
L
V
N
I
K
Chimpanzee
Pan troglodytes
XP_507733
842
94267
S515
K
S
F
S
K
D
L
S
Q
I
L
V
N
I
K
Rhesus Macaque
Macaca mulatta
XP_001091098
681
77941
P381
F
P
S
S
D
E
E
P
L
S
Q
V
L
S
G
Dog
Lupus familis
XP_535156
842
94080
S515
K
S
F
S
K
D
L
S
Q
I
L
V
N
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9X6
813
90392
S510
N
T
S
D
R
S
S
S
K
D
L
S
Q
I
L
Rat
Rattus norvegicus
NP_001102051
808
90800
S505
F
S
R
T
N
A
S
S
K
P
C
E
N
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509590
778
87501
A473
P
H
L
S
R
T
N
A
S
S
I
R
C
E
N
Chicken
Gallus gallus
XP_418573
843
94228
S515
K
S
F
S
K
D
L
S
Q
I
L
V
N
I
K
Frog
Xenopus laevis
Q66JA8
804
90630
R500
Q
P
P
S
S
P
S
R
T
N
A
S
D
R
H
Zebra Danio
Brachydanio rerio
NP_001082878
797
88820
H493
Q
P
S
T
D
T
S
H
T
S
T
D
T
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397232
868
96064
T537
S
D
I
E
P
I
L
T
Q
S
K
P
L
P
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192895
443
51775
M143
P
I
K
F
E
I
M
M
D
R
L
E
K
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
80.3
97.2
N.A.
90.5
53.9
N.A.
48.9
92.6
54
64.3
N.A.
N.A.
35.1
N.A.
30.9
Protein Similarity:
100
97.6
80.7
98.2
N.A.
93.9
68.7
N.A.
62.6
95.9
67.4
75.7
N.A.
N.A.
51
N.A.
41
P-Site Identity:
100
100
13.3
100
N.A.
20
20
N.A.
6.6
100
6.6
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
20
100
N.A.
40
33.3
N.A.
26.6
100
20
13.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
9
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% C
% Asp:
0
9
0
9
17
34
0
0
9
9
0
9
9
0
0
% D
% Glu:
0
0
0
9
9
9
9
0
0
0
0
17
0
9
0
% E
% Phe:
17
0
34
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% G
% His:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
9
9
0
0
17
0
0
0
34
9
0
0
42
0
% I
% Lys:
34
0
9
0
34
0
0
0
17
0
9
0
9
0
34
% K
% Leu:
0
0
9
0
0
0
42
0
9
0
50
0
17
0
17
% L
% Met:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
9
0
9
0
0
9
0
0
42
0
9
% N
% Pro:
17
25
9
0
9
9
0
9
0
9
0
9
0
9
0
% P
% Gln:
17
0
0
0
0
0
0
0
42
0
9
0
9
0
0
% Q
% Arg:
0
0
9
0
17
0
0
9
0
9
0
9
0
17
0
% R
% Ser:
9
42
25
59
9
9
34
50
9
34
0
17
0
17
9
% S
% Thr:
0
9
0
17
0
17
0
9
17
0
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _