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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPC1 All Species: 24.24
Human Site: S648 Identified Species: 48.48
UniProt: Q9H2F5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2F5 NP_079485.1 836 93463 S648 R T L Q G F V S K T L D S A S
Chimpanzee Pan troglodytes XP_507733 842 94267 S648 R T L Q G F V S K T L D S A S
Rhesus Macaque Macaca mulatta XP_001091098 681 77941 N504 F A N T S E T N T S D K S F S
Dog Lupus familis XP_535156 842 94080 S654 R A L Q G F V S K T L D S A S
Cat Felis silvestris
Mouse Mus musculus Q8C9X6 813 90392 A633 K T L D S A S A Q F A A S A L
Rat Rattus norvegicus NP_001102051 808 90800 S629 S S T S D C M S K T L D S A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509590 778 87501 S599 S G T S D C L S K T L D S A S
Chicken Gallus gallus XP_418573 843 94228 S654 G T L Q G F V S K T L D S V S
Frog Xenopus laevis Q66JA8 804 90630 S625 S G S S D C M S K T L D S A S
Zebra Danio Brachydanio rerio NP_001082878 797 88820 S619 N N P Q S L V S K T I D A A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397232 868 96064 N688 A A I E T Q S N Q S K Q Q Q H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192895 443 51775 I266 R E N L H L T I E I F E K R Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 80.3 97.2 N.A. 90.5 53.9 N.A. 48.9 92.6 54 64.3 N.A. N.A. 35.1 N.A. 30.9
Protein Similarity: 100 97.6 80.7 98.2 N.A. 93.9 68.7 N.A. 62.6 95.9 67.4 75.7 N.A. N.A. 51 N.A. 41
P-Site Identity: 100 100 13.3 93.3 N.A. 26.6 53.3 N.A. 53.3 86.6 53.3 53.3 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 26.6 93.3 N.A. 46.6 66.6 N.A. 60 86.6 60 66.6 N.A. N.A. 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 0 0 0 9 0 9 0 0 9 9 9 67 0 % A
% Cys: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 25 0 0 0 0 0 9 67 0 0 0 % D
% Glu: 0 9 0 9 0 9 0 0 9 0 0 9 0 0 0 % E
% Phe: 9 0 0 0 0 34 0 0 0 9 9 0 0 9 0 % F
% Gly: 9 17 0 0 34 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 9 0 0 0 0 9 0 9 9 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 67 0 9 9 9 0 0 % K
% Leu: 0 0 42 9 0 17 9 0 0 0 59 0 0 0 9 % L
% Met: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 17 0 0 0 0 17 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 42 0 9 0 0 17 0 0 9 9 9 0 % Q
% Arg: 34 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % R
% Ser: 25 9 9 25 25 0 17 67 0 17 0 0 75 0 75 % S
% Thr: 0 34 17 9 9 0 17 0 9 67 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 42 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _