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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPC1 All Species: 13.94
Human Site: T563 Identified Species: 27.88
UniProt: Q9H2F5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2F5 NP_079485.1 836 93463 T563 T G T A Q P G T Q T C S T S T
Chimpanzee Pan troglodytes XP_507733 842 94267 T563 T G T A Q P G T Q T C S T S T
Rhesus Macaque Macaca mulatta XP_001091098 681 77941 K429 N W P W T S P K D G G L G D V
Dog Lupus familis XP_535156 842 94080 T563 T G T A Q P G T Q T C S T S T
Cat Felis silvestris
Mouse Mus musculus Q8C9X6 813 90392 A558 S I S R A G A A Q P G A H T C
Rat Rattus norvegicus NP_001102051 808 90800 V553 S R K P G Q T V S S K R V S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509590 778 87501 Q521 C T S R K P G Q T G N D Q R V
Chicken Gallus gallus XP_418573 843 94228 T563 T G T A Q P G T Q T C S T S I
Frog Xenopus laevis Q66JA8 804 90630 L548 R E E C T S R L G Q A V N L K
Zebra Danio Brachydanio rerio NP_001082878 797 88820 T541 D N P E H W S T R R P R R G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397232 868 96064 D585 F S P D T L S D F D L A V A S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192895 443 51775 I191 L C N G H S L I P E V K Q E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 80.3 97.2 N.A. 90.5 53.9 N.A. 48.9 92.6 54 64.3 N.A. N.A. 35.1 N.A. 30.9
Protein Similarity: 100 97.6 80.7 98.2 N.A. 93.9 68.7 N.A. 62.6 95.9 67.4 75.7 N.A. N.A. 51 N.A. 41
P-Site Identity: 100 100 0 100 N.A. 6.6 6.6 N.A. 13.3 93.3 0 6.6 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 0 100 N.A. 33.3 20 N.A. 26.6 93.3 0 13.3 N.A. N.A. 20 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 34 9 0 9 9 0 0 9 17 0 9 9 % A
% Cys: 9 9 0 9 0 0 0 0 0 0 34 0 0 0 9 % C
% Asp: 9 0 0 9 0 0 0 9 9 9 0 9 0 9 0 % D
% Glu: 0 9 9 9 0 0 0 0 0 9 0 0 0 9 0 % E
% Phe: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % F
% Gly: 0 34 0 9 9 9 42 0 9 17 17 0 9 9 0 % G
% His: 0 0 0 0 17 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % I
% Lys: 0 0 9 0 9 0 0 9 0 0 9 9 0 0 17 % K
% Leu: 9 0 0 0 0 9 9 9 0 0 9 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 9 0 0 0 0 0 0 0 9 0 9 0 0 % N
% Pro: 0 0 25 9 0 42 9 0 9 9 9 0 0 0 0 % P
% Gln: 0 0 0 0 34 9 0 9 42 9 0 0 17 0 0 % Q
% Arg: 9 9 0 17 0 0 9 0 9 9 0 17 9 9 0 % R
% Ser: 17 9 17 0 0 25 17 0 9 9 0 34 0 42 9 % S
% Thr: 34 9 34 0 25 0 9 42 9 34 0 0 34 9 25 % T
% Val: 0 0 0 0 0 0 0 9 0 0 9 9 17 0 17 % V
% Trp: 0 9 0 9 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _