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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPC1
All Species:
12.73
Human Site:
Y474
Identified Species:
25.45
UniProt:
Q9H2F5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2F5
NP_079485.1
836
93463
Y474
L
D
R
A
H
S
D
Y
D
S
V
F
H
H
L
Chimpanzee
Pan troglodytes
XP_507733
842
94267
Y474
L
D
R
A
H
S
D
Y
D
S
V
F
H
H
L
Rhesus Macaque
Macaca mulatta
XP_001091098
681
77941
K340
R
P
K
R
K
Y
E
K
K
P
K
V
L
P
S
Dog
Lupus familis
XP_535156
842
94080
Y474
L
D
R
A
H
S
D
Y
D
S
M
F
R
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9X6
813
90392
A469
G
R
V
V
L
D
R
A
H
S
D
Y
D
S
M
Rat
Rattus norvegicus
NP_001102051
808
90800
D464
R
G
G
R
V
I
M
D
R
I
S
T
E
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509590
778
87501
V432
I
G
R
G
G
R
V
V
M
D
R
I
A
T
E
Chicken
Gallus gallus
XP_418573
843
94228
Y474
L
D
R
A
H
S
D
Y
D
N
T
F
H
Q
L
Frog
Xenopus laevis
Q66JA8
804
90630
G459
R
K
R
L
G
R
G
G
R
V
I
M
D
R
L
Zebra Danio
Brachydanio rerio
NP_001082878
797
88820
G452
R
R
R
V
G
R
G
G
R
V
L
L
D
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397232
868
96064
A496
P
V
D
S
D
T
T
A
M
S
T
T
S
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192895
443
51775
V102
Q
N
R
Q
Y
I
H
V
Q
P
L
S
M
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
80.3
97.2
N.A.
90.5
53.9
N.A.
48.9
92.6
54
64.3
N.A.
N.A.
35.1
N.A.
30.9
Protein Similarity:
100
97.6
80.7
98.2
N.A.
93.9
68.7
N.A.
62.6
95.9
67.4
75.7
N.A.
N.A.
51
N.A.
41
P-Site Identity:
100
100
0
86.6
N.A.
6.6
6.6
N.A.
6.6
80
13.3
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
20
6.6
N.A.
13.3
86.6
20
13.3
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
0
0
0
17
0
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
9
0
9
9
34
9
34
9
9
0
25
0
9
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% F
% Gly:
9
17
9
9
25
0
17
17
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
34
0
9
0
9
0
0
0
25
34
0
% H
% Ile:
9
0
0
0
0
17
0
0
0
9
9
9
0
0
0
% I
% Lys:
0
9
9
0
9
0
0
9
9
0
9
0
0
0
9
% K
% Leu:
34
0
0
9
9
0
0
0
0
0
17
9
9
0
42
% L
% Met:
0
0
0
0
0
0
9
0
17
0
9
9
9
0
9
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
9
9
0
0
0
0
0
0
0
17
0
0
0
9
0
% P
% Gln:
9
0
0
9
0
0
0
0
9
0
0
0
0
9
9
% Q
% Arg:
34
17
67
17
0
25
9
0
25
0
9
0
9
17
0
% R
% Ser:
0
0
0
9
0
34
0
0
0
42
9
9
9
9
9
% S
% Thr:
0
0
0
0
0
9
9
0
0
0
17
17
0
9
0
% T
% Val:
0
9
9
17
9
0
9
17
0
17
17
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
34
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _