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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC38A1 All Species: 18.18
Human Site: S49 Identified Species: 40
UniProt: Q9H2H9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2H9 NP_001070952.1 487 54048 S49 K F I S D R E S R R S L T N S
Chimpanzee Pan troglodytes XP_001164465 474 52848 I39 T E V E N G Q I N S K F I S D
Rhesus Macaque Macaca mulatta XP_001094371 487 53993 S49 K F I S D R E S R R S L T N S
Dog Lupus familis XP_534827 487 54152 S49 K F I S D R E S R R S L T N S
Cat Felis silvestris
Mouse Mus musculus Q8K2P7 485 53777 S49 K F I S D R E S R R S L T N S
Rat Rattus norvegicus Q9JM15 485 53828 S49 K F I S D R E S R R S L T N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506213 293 33141
Chicken Gallus gallus Q5F468 501 55512 Q50 A D M D P E N Q N F L L D S N
Frog Xenopus laevis Q6DFE7 452 48963 G17 A D Y S W D A G E R A R L L Q
Zebra Danio Brachydanio rerio Q5SPB1 504 55813 Q52 S D V E A E S Q N F L S D H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39981 480 53305 N45 S Q G Q N S L N I I T P D M D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 98.9 96.7 N.A. 93 93.6 N.A. 52.3 50.7 24.2 50 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.4 99.1 97.7 N.A. 96.5 96.5 N.A. 55.2 69.4 44.7 69.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 6.6 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 0 26.6 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 0 0 10 0 10 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 28 0 10 46 10 0 0 0 0 0 0 28 0 19 % D
% Glu: 0 10 0 19 0 19 46 0 10 0 0 0 0 0 0 % E
% Phe: 0 46 0 0 0 0 0 0 0 19 0 10 0 0 0 % F
% Gly: 0 0 10 0 0 10 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 0 46 0 0 0 0 10 10 10 0 0 10 0 0 % I
% Lys: 46 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 19 55 10 10 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 19 0 10 10 28 0 0 0 0 46 10 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 10 0 10 0 0 10 19 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 46 0 0 46 55 0 10 0 0 0 % R
% Ser: 19 0 0 55 0 10 10 46 0 10 46 10 0 19 46 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 10 0 46 0 0 % T
% Val: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _