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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC38A1
All Species:
15.76
Human Site:
T259
Identified Species:
34.67
UniProt:
Q9H2H9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2H9
NP_001070952.1
487
54048
T259
S
T
I
S
A
N
S
T
N
A
D
T
C
T
P
Chimpanzee
Pan troglodytes
XP_001164465
474
52848
E249
Q
I
P
C
I
V
P
E
L
N
S
T
I
S
A
Rhesus Macaque
Macaca mulatta
XP_001094371
487
53993
T259
S
T
I
S
A
N
S
T
N
A
D
M
C
T
P
Dog
Lupus familis
XP_534827
487
54152
T259
S
T
I
S
A
N
L
T
N
P
D
M
C
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2P7
485
53777
T259
S
T
V
S
A
N
V
T
D
A
C
T
P
K
Y
Rat
Rattus norvegicus
Q9JM15
485
53828
T259
S
T
V
S
A
N
V
T
D
A
C
T
P
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506213
293
33141
V68
V
D
G
R
I
L
V
V
G
V
T
F
C
I
I
Chicken
Gallus gallus
Q5F468
501
55512
A260
I
N
A
T
L
I
N
A
T
L
A
P
F
A
D
Frog
Xenopus laevis
Q6DFE7
452
48963
S227
P
S
H
E
I
S
S
S
S
S
S
W
L
A
V
Zebra Danio
Brachydanio rerio
Q5SPB1
504
55813
P262
I
T
V
N
V
S
Q
P
P
Q
T
N
N
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39981
480
53305
M255
L
K
L
S
D
F
F
M
K
A
T
I
F
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
98.9
96.7
N.A.
93
93.6
N.A.
52.3
50.7
24.2
50
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.4
99.1
97.7
N.A.
96.5
96.5
N.A.
55.2
69.4
44.7
69.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
80
N.A.
53.3
53.3
N.A.
6.6
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
93.3
80
N.A.
66.6
66.6
N.A.
6.6
13.3
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
46
0
0
10
0
46
10
0
0
19
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
19
0
37
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
19
0
28
0
0
0
10
% D
% Glu:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
10
19
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
10
28
0
28
10
0
0
0
0
0
10
10
10
10
% I
% Lys:
0
10
0
0
0
0
0
0
10
0
0
0
0
19
0
% K
% Leu:
10
0
10
0
10
10
10
0
10
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
19
0
0
0
% M
% Asn:
0
10
0
10
0
46
10
0
28
10
0
10
10
0
0
% N
% Pro:
10
0
10
0
0
0
10
10
10
10
0
10
19
0
28
% P
% Gln:
10
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
46
10
0
55
0
19
28
10
10
10
19
0
0
19
10
% S
% Thr:
0
55
0
10
0
0
0
46
10
0
28
37
0
28
10
% T
% Val:
10
0
28
0
10
10
28
10
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _