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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC38A1 All Species: 12.73
Human Site: Y345 Identified Species: 28
UniProt: Q9H2H9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2H9 NP_001070952.1 487 54048 Y345 Q S D L L H K Y Q S K D D I L
Chimpanzee Pan troglodytes XP_001164465 474 52848 D335 F G Y L T F Y D N V Q S D L L
Rhesus Macaque Macaca mulatta XP_001094371 487 53993 Y345 Q S D L L H K Y Q S K D D I L
Dog Lupus familis XP_534827 487 54152 Y345 Q S D L L H K Y Q S K D D I L
Cat Felis silvestris
Mouse Mus musculus Q8K2P7 485 53777 S345 D L L H K Y Q S T G D I L I L
Rat Rattus norvegicus Q9JM15 485 53828 S345 D L L H K Y Q S T G D I L I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506213 293 33141 A154 A L P T I A F A F V C H P S V
Chicken Gallus gallus Q5F468 501 55512 Y346 L F G Y L T F Y G R V E S E L
Frog Xenopus laevis Q6DFE7 452 48963 V313 S D D I A V A V A R A F I I L
Zebra Danio Brachydanio rerio Q5SPB1 504 55813 E348 L T F N E A V E P E L L H T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39981 480 53305 L341 T A I N I A R L C F G F N M L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 98.9 96.7 N.A. 93 93.6 N.A. 52.3 50.7 24.2 50 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.4 99.1 97.7 N.A. 96.5 96.5 N.A. 55.2 69.4 44.7 69.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 100 N.A. 13.3 13.3 N.A. 0 20 20 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 26.6 26.6 N.A. 13.3 26.6 26.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 10 28 10 10 10 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % C
% Asp: 19 10 37 0 0 0 0 10 0 0 19 28 37 0 0 % D
% Glu: 0 0 0 0 10 0 0 10 0 10 0 10 0 10 0 % E
% Phe: 10 10 10 0 0 10 19 0 10 10 0 19 0 0 0 % F
% Gly: 0 10 10 0 0 0 0 0 10 19 10 0 0 0 0 % G
% His: 0 0 0 19 0 28 0 0 0 0 0 10 10 0 0 % H
% Ile: 0 0 10 10 19 0 0 0 0 0 0 19 10 55 0 % I
% Lys: 0 0 0 0 19 0 28 0 0 0 28 0 0 0 0 % K
% Leu: 19 28 19 37 37 0 0 10 0 0 10 10 19 10 82 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 19 0 0 0 0 10 0 0 0 10 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 10 0 0 0 10 0 0 % P
% Gln: 28 0 0 0 0 0 19 0 28 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 19 0 0 0 0 0 % R
% Ser: 10 28 0 0 0 0 0 19 0 28 0 10 10 10 0 % S
% Thr: 10 10 0 10 10 10 0 0 19 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 10 10 10 0 19 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 19 10 37 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _