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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCL3
All Species:
18.48
Human Site:
S227
Identified Species:
33.89
UniProt:
Q9H2J4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2J4
NP_076970.1
239
27614
S227
L
L
S
S
V
R
R
S
V
L
M
K
R
D
S
Chimpanzee
Pan troglodytes
XP_525834
239
27568
S227
L
L
S
S
V
R
R
S
V
L
M
K
R
D
S
Rhesus Macaque
Macaca mulatta
XP_001097346
237
27366
S225
L
L
S
S
V
R
R
S
V
F
M
R
R
G
S
Dog
Lupus familis
XP_531782
240
27598
S228
L
L
S
S
V
R
C
S
I
P
T
R
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVF2
240
27563
P228
L
L
S
S
V
R
G
P
V
P
M
R
R
D
S
Rat
Rattus norvegicus
Q4KLJ8
240
27681
P228
L
L
S
S
V
R
D
P
V
P
M
R
R
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515043
192
22275
P181
I
K
A
Q
F
I
G
P
L
V
F
G
G
M
N
Chicken
Gallus gallus
NP_001025983
240
27758
C228
L
M
S
S
I
R
A
C
V
P
T
R
G
E
S
Frog
Xenopus laevis
NP_001086629
237
27418
S225
L
M
T
S
I
R
T
S
I
P
T
K
K
D
S
Zebra Danio
Brachydanio rerio
Q6P268
239
27638
S225
L
M
T
S
I
R
C
S
A
N
T
H
R
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8MR62
240
27421
L229
P
Q
I
R
D
K
M
L
A
D
L
E
D
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794769
241
27321
Q230
N
I
F
S
G
R
N
Q
N
V
D
D
S
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12017
286
32775
K264
I
R
S
G
I
R
G
K
F
N
V
G
I
G
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
94.9
92
N.A.
89.5
87.9
N.A.
71.5
80.8
77.8
74
N.A.
47.9
N.A.
N.A.
53.1
Protein Similarity:
100
100
97
95.8
N.A.
95.8
95
N.A.
76.9
91.2
90.7
87.8
N.A.
71.2
N.A.
N.A.
72.2
P-Site Identity:
100
100
80
66.6
N.A.
73.3
73.3
N.A.
0
40
46.6
40
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
86.6
80
N.A.
80
80
N.A.
33.3
66.6
80
60
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
16
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
8
8
8
8
62
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
0
0
8
0
8
0
0
0
8
8
8
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
24
0
0
0
0
16
16
16
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
16
8
8
0
31
8
0
0
16
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
8
0
8
0
0
0
24
8
8
0
% K
% Leu:
70
47
0
0
0
0
0
8
8
16
8
0
0
0
0
% L
% Met:
0
24
0
0
0
0
8
0
0
0
39
0
0
8
0
% M
% Asn:
8
0
0
0
0
0
8
0
8
16
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
24
0
39
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
85
24
0
0
0
0
39
54
0
0
% R
% Ser:
0
0
62
77
0
0
0
47
0
0
0
0
8
0
70
% S
% Thr:
0
0
16
0
0
0
8
0
0
0
31
0
0
0
0
% T
% Val:
0
0
0
0
47
0
0
0
47
16
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _