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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCL3 All Species: 21.52
Human Site: S25 Identified Species: 39.44
UniProt: Q9H2J4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2J4 NP_076970.1 239 27614 S25 G I L P P K E S L K E L E E E
Chimpanzee Pan troglodytes XP_525834 239 27568 S25 G I L P P K E S L K E L E E E
Rhesus Macaque Macaca mulatta XP_001097346 237 27366 R25 G I L P P K E R L K E L E E E
Dog Lupus familis XP_531782 240 27598 S25 G I L P S K E S L K D L E K E
Cat Felis silvestris
Mouse Mus musculus Q8BVF2 240 27563 S25 G I L P P K E S L K E L E E E
Rat Rattus norvegicus Q4KLJ8 240 27681 S25 G I L P P K E S L K E L E E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515043 192 22275
Chicken Gallus gallus NP_001025983 240 27758 N25 G I L P P K E N R E E Q E R A
Frog Xenopus laevis NP_001086629 237 27418 K25 G I L P P K E K P Q D E E E E
Zebra Danio Brachydanio rerio Q6P268 239 27638 T25 G I L P P K E T P V E E E E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MR62 240 27421 K25 G I I G P K A K E A E I T E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794769 241 27321 A25 G I I P E K E A T V T E D Q I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12017 286 32775 P34 G V I P E R A P S P T A K L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.9 92 N.A. 89.5 87.9 N.A. 71.5 80.8 77.8 74 N.A. 47.9 N.A. N.A. 53.1
Protein Similarity: 100 100 97 95.8 N.A. 95.8 95 N.A. 76.9 91.2 90.7 87.8 N.A. 71.2 N.A. N.A. 72.2
P-Site Identity: 100 100 93.3 80 N.A. 100 100 N.A. 0 60 66.6 66.6 N.A. 40 N.A. N.A. 33.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 100 100 N.A. 0 73.3 80 80 N.A. 60 N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 16 8 0 8 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 16 0 8 0 16 % D
% Glu: 0 0 0 0 16 0 77 0 8 8 62 24 70 62 62 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 93 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 85 24 0 0 0 0 0 0 0 0 8 0 0 8 % I
% Lys: 0 0 0 0 0 85 0 16 0 47 0 0 8 8 0 % K
% Leu: 0 0 70 0 0 0 0 0 47 0 0 47 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 85 70 0 0 8 16 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 0 % Q
% Arg: 0 0 0 0 0 8 0 8 8 0 0 0 0 8 0 % R
% Ser: 0 0 0 0 8 0 0 39 8 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 8 0 16 0 8 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 16 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _