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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNKS2 All Species: 44.24
Human Site: S59 Identified Species: 81.11
UniProt: Q9H2K2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2K2 NP_079511.1 1166 126918 S59 R D T A G R K S T P L H F A A
Chimpanzee Pan troglodytes XP_001137443 1327 142033 S217 K D M A G R K S S P L H F A A
Rhesus Macaque Macaca mulatta XP_001090358 1327 142132 S217 K D M A G R K S S P L H F A A
Dog Lupus familis XP_534962 1316 141794 S209 R D T A G R K S T P L H F A A
Cat Felis silvestris
Mouse Mus musculus NP_001157107 1166 126725 S59 R D T A G R K S T P L H F A A
Rat Rattus norvegicus NP_001101077 1166 126761 S59 R D T A G R K S T P L H F A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508887 1320 142724 S210 K D M A G R K S S P L H F A A
Chicken Gallus gallus Q5F478 990 107379 F17 P P L V Q A I F S G D P E E I
Frog Xenopus laevis NP_001088420 1303 140252 S193 K D M A G R K S T P L H F A A
Zebra Danio Brachydanio rerio Q502K3 1071 114412 P44 L D Q E R R T P L H A A A W L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651410 1181 127927 S58 R D T A G R K S T P L H F A A
Honey Bee Apis mellifera XP_396483 1166 127309 S57 R D T A G R K S T P L H F A A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001186587 1157 126547 S59 R D T A G R K S S P L H F A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.5 72.5 87.9 N.A. 97.2 97.2 N.A. 72.5 24 73.1 23.3 N.A. 65.3 70.6 N.A. 69.5
Protein Similarity: 100 80.3 80.3 88.2 N.A. 98.8 99 N.A. 80.5 40.3 81.3 38.9 N.A. 79.8 83 N.A. 83.1
P-Site Identity: 100 80 80 100 N.A. 100 100 N.A. 80 0 86.6 13.3 N.A. 100 100 N.A. 93.3
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 100 N.A. 93.3 6.6 93.3 13.3 N.A. 100 100 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 85 0 8 0 0 0 0 8 8 8 85 85 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 93 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 85 0 0 % F
% Gly: 0 0 0 0 85 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 85 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % I
% Lys: 31 0 0 0 0 0 85 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 8 0 0 0 0 0 8 0 85 0 0 0 8 % L
% Met: 0 0 31 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 0 0 0 8 0 85 0 8 0 0 0 % P
% Gln: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 54 0 0 0 8 93 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 85 39 0 0 0 0 0 0 % S
% Thr: 0 0 54 0 0 0 8 0 54 0 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _