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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DPH5
All Species:
5.76
Human Site:
S268
Identified Species:
8.44
UniProt:
Q9H2P9
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2P9
NP_001070862.1
285
31651
S268
P
M
E
M
E
M
L
S
L
F
S
I
P
E
N
Chimpanzee
Pan troglodytes
XP_001137239
237
25999
L221
M
E
M
E
M
L
S
L
F
S
I
P
E
N
S
Rhesus Macaque
Macaca mulatta
XP_001109026
285
31643
N268
P
I
E
M
E
M
L
N
L
F
S
I
P
E
N
Dog
Lupus familis
XP_854914
292
32660
S268
P
L
E
M
E
M
L
S
L
F
S
I
P
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWQ0
281
31226
M264
G
N
L
H
P
L
E
M
E
M
L
S
L
F
S
Rat
Rattus norvegicus
NP_001017449
281
31171
M264
G
N
L
H
P
L
E
M
E
M
L
S
L
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506442
275
30312
H259
L
I
I
T
G
T
M
H
P
L
E
V
D
M
L
Chicken
Gallus gallus
XP_422306
285
31828
L268
L
E
L
E
M
L
K
L
F
S
V
D
S
S
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007387
288
32021
L268
L
E
V
D
M
L
K
L
F
S
S
P
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524452
281
31601
E265
E
M
H
P
L
E
V
E
F
L
Q
Q
Y
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496427
274
30984
P258
P
L
H
S
L
I
I
P
G
E
T
H
P
L
E
Sea Urchin
Strong. purpuratus
XP_783189
285
31755
Q269
V
E
L
E
M
L
K
Q
F
A
V
T
P
S
I
Poplar Tree
Populus trichocarpa
XP_002300714
285
31836
M269
I
E
E
E
M
L
N
M
Y
K
L
K
G
E
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81769
277
30772
T260
C
L
V
I
V
G
E
T
H
P
V
E
E
E
M
Baker's Yeast
Sacchar. cerevisiae
P32469
300
33829
L265
E
L
E
L
E
Y
L
L
E
F
A
D
D
K
E
Red Bread Mold
Neurospora crassa
Q7S949
287
32194
R266
E
L
E
H
D
F
V
R
E
F
A
V
N
K
E
Conservation
Percent
Protein Identity:
100
83.1
96.8
88.3
N.A.
90.5
90.8
N.A.
80.3
79.6
N.A.
75
N.A.
61.4
N.A.
60.7
63.1
Protein Similarity:
100
83.1
99.6
94.1
N.A.
96.1
96.4
N.A.
92.2
92.2
N.A.
88.5
N.A.
76.4
N.A.
76.4
83.5
P-Site Identity:
100
0
86.6
86.6
N.A.
0
0
N.A.
0
6.6
N.A.
6.6
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
13.3
13.3
N.A.
20
13.3
N.A.
13.3
N.A.
13.3
N.A.
40
13.3
Percent
Protein Identity:
58.9
N.A.
N.A.
57.8
52.6
57.1
Protein Similarity:
80.3
N.A.
N.A.
76.8
71.3
73.8
P-Site Identity:
13.3
N.A.
N.A.
6.6
26.6
13.3
P-Site Similarity:
26.6
N.A.
N.A.
26.6
53.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
13
0
0
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
0
0
0
0
0
0
13
13
7
0
% D
% Glu:
19
32
38
25
25
7
19
7
25
7
7
7
19
25
19
% E
% Phe:
0
0
0
0
0
7
0
0
32
32
0
0
0
13
0
% F
% Gly:
13
0
0
0
7
7
0
0
7
0
0
0
7
7
0
% G
% His:
0
0
13
19
0
0
0
7
7
0
0
7
0
0
0
% H
% Ile:
7
13
7
7
0
7
7
0
0
0
7
19
0
0
7
% I
% Lys:
0
0
0
0
0
0
19
0
0
7
0
7
0
13
0
% K
% Leu:
19
32
25
7
13
44
25
25
19
13
19
0
13
7
13
% L
% Met:
7
13
7
19
32
19
7
19
0
13
0
0
0
7
7
% M
% Asn:
0
13
0
0
0
0
7
7
0
0
0
0
7
7
25
% N
% Pro:
25
0
0
7
13
0
0
7
7
7
0
13
32
0
7
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
7
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
7
13
0
19
25
13
7
13
25
% S
% Thr:
0
0
0
7
0
7
0
7
0
0
7
7
0
0
0
% T
% Val:
7
0
13
0
7
0
13
0
0
0
19
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _