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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DPH5 All Species: 9.39
Human Site: S276 Identified Species: 13.78
UniProt: Q9H2P9 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H2P9 NP_001070862.1 285 31651 S276 L F S I P E N S S E S Q S I N
Chimpanzee Pan troglodytes XP_001137239 237 25999 S229 F S I P E N S S E S Q S I N G
Rhesus Macaque Macaca mulatta XP_001109026 285 31643 S276 L F S I P E N S S E S Q S I D
Dog Lupus familis XP_854914 292 32660 S276 L F S I P D N S S E S S D G I
Cat Felis silvestris
Mouse Mus musculus Q9CWQ0 281 31226 I272 E M L S L F S I P E S Q S T D
Rat Rattus norvegicus NP_001017449 281 31171 I272 E M L S L F S I P E S Q S T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506442 275 30312 K267 P L E V D M L K I F S V A E E
Chicken Gallus gallus XP_422306 285 31828 F276 F S V D S S N F E N N A F Q K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007387 288 32021 K276 F S S P E G L K S L K M T D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524452 281 31601 S273 F L Q Q Y A P S I K L D D Y N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_496427 274 30984 V266 G E T H P L E V D M L E T F R
Sea Urchin Strong. purpuratus XP_783189 285 31755 F277 F A V T P S I F D A L L A E S
Poplar Tree Populus trichocarpa XP_002300714 285 31836 I277 Y K L K G E S I D H K D H R T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81769 277 30772 L268 H P V E E E M L E F Y K Y K S
Baker's Yeast Sacchar. cerevisiae P32469 300 33829 K273 E F A D D K E K F G K D V A N
Red Bread Mold Neurospora crassa Q7S949 287 32194 N274 E F A V N K E N W D R I W K A
Conservation
Percent
Protein Identity: 100 83.1 96.8 88.3 N.A. 90.5 90.8 N.A. 80.3 79.6 N.A. 75 N.A. 61.4 N.A. 60.7 63.1
Protein Similarity: 100 83.1 99.6 94.1 N.A. 96.1 96.4 N.A. 92.2 92.2 N.A. 88.5 N.A. 76.4 N.A. 76.4 83.5
P-Site Identity: 100 6.6 93.3 66.6 N.A. 26.6 26.6 N.A. 6.6 6.6 N.A. 13.3 N.A. 13.3 N.A. 6.6 6.6
P-Site Similarity: 100 13.3 100 73.3 N.A. 40 40 N.A. 20 13.3 N.A. 26.6 N.A. 20 N.A. 26.6 20
Percent
Protein Identity: 58.9 N.A. N.A. 57.8 52.6 57.1
Protein Similarity: 80.3 N.A. N.A. 76.8 71.3 73.8
P-Site Identity: 6.6 N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: 13.3 N.A. N.A. 20 26.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 13 0 0 7 0 0 0 7 0 7 13 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 13 7 0 0 19 7 0 19 13 7 19 % D
% Glu: 25 7 7 7 19 25 19 0 19 32 0 7 0 13 7 % E
% Phe: 32 32 0 0 0 13 0 13 7 13 0 0 7 7 0 % F
% Gly: 7 0 0 0 7 7 0 0 0 7 0 0 0 7 7 % G
% His: 7 0 0 7 0 0 0 0 0 7 0 0 7 0 0 % H
% Ile: 0 0 7 19 0 0 7 19 13 0 0 7 7 13 7 % I
% Lys: 0 7 0 7 0 13 0 19 0 7 19 7 0 13 7 % K
% Leu: 19 13 19 0 13 7 13 7 0 7 19 7 0 0 0 % L
% Met: 0 13 0 0 0 7 7 0 0 7 0 7 0 0 0 % M
% Asn: 0 0 0 0 7 7 25 7 0 7 7 0 0 7 19 % N
% Pro: 7 7 0 13 32 0 7 0 13 0 0 0 0 0 0 % P
% Gln: 0 0 7 7 0 0 0 0 0 0 7 25 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 7 0 0 7 7 % R
% Ser: 0 19 25 13 7 13 25 32 25 7 38 13 25 0 19 % S
% Thr: 0 0 7 7 0 0 0 0 0 0 0 0 13 13 7 % T
% Val: 0 0 19 13 0 0 0 7 0 0 0 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % W
% Tyr: 7 0 0 0 7 0 0 0 0 0 7 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _